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| Size/SKU | Availability | Price |
|---|---|---|
5 mg | Available to ship TODAYfromMILWAUKEE | $70.60 $60.01 |
25 mg | Available to ship TODAYfromMILWAUKEE | $288.00 $244.80 |
About This Item
Empirical Formula (Hill Notation):
C20H22BrFN2O3S
Molecular Weight:
469.37
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
$60.01
List Price$70.60Save 15%Web-Only Promotion
Available to ship TODAYDetails
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
SMILES string
FC1=CC=C(NC(O[C@@H]2C[C@H]([C@@H]3[C@H]4O3)[N+](C)(C)[C@H]4C2)=O)C(C5=CC=CS5)=C1.[Br-]
Biochem/physiol Actions
BS46 is a highly potent and selective muscarinic acetylcholine receptor antagonist that exhibits 33-fold preference for M3R (M3 muscarinic acetylcholine receptor) over M2R. It fully inhibits carbachol-induced inositol monophosphate accumulation as well as ?-arrestin recruitment at M3Rs. BS46 exhibits 100,000-fold selectivity for muscarinic receptors against 21 aminergic and peptidergic GPCRs.
highly potent and selective M3 muscarinic acetylcholine receptor (M3R) antagonist that exhibits 33-fold preference for M3R over M2R
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This Item | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: 2 mg/mL, clear | solubility DMSO: >10 mg/mL | solubility DMSO: 2 mg/mL, clear | solubility DMSO: 2 mg/mL, clear |
| color white to beige | color white | color white to beige | color white to beige |
Storage Class
11 - Combustible Solids
wgk
WGK 3
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