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SML2972

Cyclopentenyl uracil

≥98% (HPLC)

Synonym(s):

1-[(1R,4R,5S)-4,5-Dihydroxy-3-(hydroxymethyl)-2-cyclopenten-1-yl]-2,4(1H,3H)-pyrimidinedione, Cyclopentenyluracil, Cyclopentenyluridine, NSC 375574

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Size/SKUAvailabilityPrice
5 mg

Available to ship TODAYfromMILWAUKEE

$100.00
25 mg

Available to ship TODAYfromMILWAUKEE

$404.00

About This Item

Empirical Formula (Hill Notation):
C10H12N2O5
CAS Number:
Molecular Weight:
240.21
UNSPSC Code:
51111800
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

$100.00


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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

[nH]1[c]([n](cc[c]1=O)[C@H]2[C@@H]([C@@H](C(=C2)CO)O)O)=O

InChI

1S/C10H12N2O5/c13-4-5-3-6(9(16)8(5)15)12-2-1-7(14)11-10(12)17/h1-3,6,8-9,13,15-16H,4H2,(H,11,14,17)/t6-,8-,9+/m1/s1

InChI key

FCWVOJUKQSHZIV-VDAHYXPESA-N

Biochem/physiol Actions

Cyclopentenyl uracil is a non-cytotoxic inhibitor of uridine kinase that act as a potent inhibitor of pyrimidine salvage in the intact mouse. Combination of Cyclopentenyl uracil with GSK983 significantly reduces viral infection of dengue serotype 2 (DENV-2) strain 16681 in cultures of the A549 lung carcinoma cell line. Cyclopentenyl uracil in combination with GSK983 enhances therapeutic index of viral RdRp inhibitor R1479.
non-cytotoxic inhibitor of uridine kinase that act as a potent inhibitor of pyrimidine salvage

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This Item
SML0376SML1513SML1484
description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

description

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: >2 mg/mL (warmed)

solubility

DMSO: 5 mg/mL, clear (warmed)

solubility

H2O: 2 mg/mL, clear (warmed)

color

white to beige

color

light yellow to light brown

color

white to beige

color

white to beige


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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