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SRP2102

TNFα, low endotoxin, His tagged human

recombinant, expressed in E. coli, ≥80% (SDS-PAGE)

Synonym(s):

DIF, TNF-alpha, TNFA, TNFSF2

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10 μg
Usually ships in 2 weeks.
$469.00

About This Item

NACRES:
NA.26
UNSPSC Code:
12352200
Form:
frozen liquid
Assay:
≥80% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in E. coli
Mol wt:
~21 kDa

$469.00


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biological source

human

recombinant

expressed in E. coli

assay

≥80% (SDS-PAGE)

form

frozen liquid

mol wt

~21 kDa

packaging

pkg of 10 μg

storage condition

avoid repeated freeze/thaw cycles

concentration

1250 μg/mL

color

clear colorless

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... TNF(7124)

General description

Tumor necrosis factor α (TNFα or TNFSF2) is encoded by the gene mapped to human chromosome 6p21.33.

Biochem/physiol Actions

Tumor necrosis factor α (TNFα or TNFSF2) is produced by many different cell types including activated monocytes, fibroblasts, endothelial cells, macrophages, T-cells, B-lymphocytes, granulocytes, smooth muscle cells, eosinophilis, chondrocytes and other cell types. It functions as a cytokine involved in cell proliferation, differentiation, apoptosis, lipid metabolism and coagulation. High level of TNFα leads to the development of inflammatory responses that are hallmarks of many diseases including autoimmune diseases, insulin resistance and cancer. The active form of TNFα (18 kDa) is generated by the cleavage of an Ala-Val bond between residues 76-77 of the precursor protein.

Physical form

Clear and colorless frozen liquid solution

Preparation Note

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

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H8916T6674T7924
description

recombinant, expressed in E. coli, ≥80% (SDS-PAGE)

description

Xeno-free, recombinant, expressed in HEK 293 cells, suitable for cell culture

description

TNF-α, recombinant, expressed in E. coli, powder, suitable for cell culture

description

TGF-α, recombinant, expressed in E. coli, powder, suitable for cell culture

biological source

human

biological source

human

biological source

human

biological source

human

assay

≥80% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

assay

≥97% (SDS-PAGE)

assay

≥98% (SDS-PAGE and HPLC)

recombinant

expressed in E. coli

recombinant

expressed in HEK 293 cells

recombinant

expressed in E. coli

recombinant

expressed in E. coli

concentration

1250 μg/mL

concentration

-

concentration

-

concentration

-

mol wt

~21 kDa

mol wt

~17.4 kDa, 17 kDa (glycosylated)

mol wt

~17.4 kDa

mol wt

5.5 kDa

form

frozen liquid

form

lyophilized powder

form

powder

form

powder


Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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