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SRP6003

Procalcitonin human

recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC)

Synonym(s):

CALC1, CALCA, CGRP, Calcitonin

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10 μg
Usually ships in 2 weeks.
$414.00

About This Item

CAS Number:
1476823-80-9
NACRES:
NA.32
UNSPSC Code:
51111800

$414.00

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biological source

human

recombinant

expressed in E. coli

assay

≥97% (HPLC), ≥97% (SDS-PAGE)

form

lyophilized

potency

80 ng/mL

mol wt

12.796 kDa

packaging

pkg of 10 μg

technique(s)

cell culture | mammalian: suitable

impurities

Endotoxin, tested

NCBI accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... N/A(796)

General description

The gene CALC1 (calcitonin 1) is mapped to human chromosome 11. CALC1 encodes for preprocalcitonin. Preprocalcitonin is cleaved by endopeptidase at the amino-terminal to produce procalcitonin. Procalcitonin works as a peptide hormone and is mainly produced by the C cells of the thyroid and certain endocrine cells of the lung. Under normal expression conditions, procalcitonin is immediately cleaved into three specific fragments, an N terminal residue, calcitonin and katacalcin. Recombinant human procalcitonin produced in Escherichia coli is a single, non-glycosylated, polypeptide chain containing 116 amino acids with a molecular weight of 12,796 Daltons.

Application

Procalcitonin human has been used in in vitro vascular permeability assay.

Biochem/physiol Actions

Procalcitonin is a prohormone of calcitonin. Levels of unprocessed procalcitonin rise significantly after bacterial infection, trauma or shock. Procalcitonin is also associated with systemic complications in humans suffering from acute pancreatitis.

Physical form

Lyophilized from a 10 mM sodium phosphate buffer, pH 7.5.

Preparation Note

Centrifuge the vial prior to opening. Reconstitute in sterile H?O to a concentration of 0.1 mg/ml.

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This Item
T3535Y0000632C7113
Procalcitonin human recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC)

Sigma-Aldrich

SRP6003

Procalcitonin human

Calcitonin human ≥97% (HPLC), powder

Sigma-Aldrich

T3535

Calcitonin human

vibrant-m

Y0000632

Calcitonin-Gly

Anti-Calcitonin Gene-Related Peptide antibody, Mouse monoclonal clone 4901, purified from hybridoma cell culture

Sigma-Aldrich

C7113

Anti-Calcitonin Gene-Related Peptide antibody, Mouse monoclonal

description

recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC)

description

≥97% (HPLC), powder

description

European Pharmacopoeia (EP) Reference Standard

description

clone 4901, purified from hybridoma cell culture

recombinant

expressed in E. coli

recombinant

-

recombinant

-

recombinant

-

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

radioimmunoassay: suitable, neutralization: suitable, immunocytochemistry: suitable, indirect ELISA: 0.5 μg/mL using rat α-CGRP

assay

≥97% (SDS-PAGE), ≥97% (HPLC)

assay

≥97% (HPLC)

assay

-

assay

-

biological source

human

biological source

synthetic (organic)

biological source

-

biological source

mouse

form

lyophilized

form

powder

form

-

form

buffered aqueous solution

Gene Information

human ... N/A(796)

Gene Information

human ... CALCA(796)

Gene Information

-

Gene Information

human ... CALCA(796)
rat ... Calca(24241)

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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