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T1126

Thyroglobulin from porcine thyroid gland

powder

Synonym(s):

TG human

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Size/SKUAvailabilityPrice
100 mg

Available to ship TODAYfromMILWAUKEE

$274.00
500 mg

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$789.00
1 g

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$1,370.00

About This Item

CAS Number:
UNSPSC Code:
12352202
EC Number:
232-721-3
NACRES:
NA.61
MDL number:
Form:
powder
Biological source:
Porcine thyroid
Mol wt:
~670 kDa

$274.00


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biological source

Porcine thyroid

Quality Segment

form

powder

mol wt

~670 kDa

composition

Iodine, ≥0.3%

nitrogen analysis

14.0-17.5% total

technique(s)

protein purification: suitable

ash

≤4%

pI 

4.58

UniProt accession no.

storage temp.

−20°C

Gene Information

pig ... TG(100156471)

Biochem/physiol Actions

Thyroglobulin has been shown to regulate the transcription of iodide porters including sodium iodide symporter and pendrin.
Thyroglobulin is a major protein involved with iodine metabolism. It consists of an iodine-containing protein that is stored in the thyroid gland and is converted into circulating thyroxines when the thyroid is stimulated by TSH (Thyroid Stimulating Hormone) from the pituitary. Thyroglobulin is often used as a carrier protein for the production of antibodies. Its advantage as a carrier protein comes from its large number of tyrosine residues that can be used for conjugation using the diazo reaction.

Preparation Note

When reconstituted in water (20 mg/ml), a turbid solution with some insolubles is observed.

Other Notes

Electrophoretically heterogeneous.

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T9145I5523SAB4701013
description

powder

description

(For Gel Filtration Chromatography)

description

powder, ≥27 USP units/mg

description

clone 2H11

technique(s)

protein purification: suitable

technique(s)

bioconjugation: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

immunohistochemistry: 10 μg/mL

biological source

Porcine thyroid

biological source

bovine thyroid

biological source

Porcine pancreas

biological source

mouse

form

powder

form

powder

form

powder

form

buffered aqueous solution

mol wt

~670 kDa

mol wt

~670 kDa

mol wt

-

mol wt

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

UniProt accession no.

F1RRV3

UniProt accession no.

P01267

UniProt accession no.

P01315

UniProt accession no.

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



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