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T2205

TRKC (507-end), active, His tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):

NTRK3, gp145(trkC)

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10 μg
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$432.00

About This Item

NACRES:
NA.32
UNSPSC Code:
12352200
Specific activity:
20-28 nmol/min·mg
Assay:
≥70% (SDS-PAGE)
Recombinant:
expressed in baculovirus infected Sf9 cells

$432.00


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recombinant

expressed in baculovirus infected Sf9 cells

Quality Segment

product line

PRECISIO® Kinase

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

20-28 nmol/min·mg

mol wt

~38 kDa

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... NTRK3(4916)

Biochem/physiol Actions

TRKC is a member of the TRK family of tyrosine kinase receptors and is the high affinity catalytic receptor for the neurotrophin NT-3 (neurotrophin-3). TRKC mediates the multiple cellular effects of the NT-3 neurotrophic factor, which includes neuronal differentiation and survival. TRKC has been implicated in insulin signaling pathway through interactions with the MUSK protein receptor and the VEGF receptor. Mutations in the TRKC gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.

Physical form

Supplied in 50 mM sodium phosphate, pH 7.0, with 150 mM imidazole, 0.1 mM PMSF, 2 mM DTT, and 25% glycerol.

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item
SRP0352SAB1306628T2080
description

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

description

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE)

description

purified immunoglobulin, buffered aqueous solution

description

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Gene Information

human ... NTRK3(4916)

Gene Information

human ... NTRK3(4916)

Gene Information

human ... NTRK3(4916)

Gene Information

human ... NTRK2(4915)

assay

≥70% (SDS-PAGE)

assay

≥70% (SDS-PAGE)

assay

-

assay

≥70% (SDS-PAGE)

specific activity

20-28 nmol/min·mg

specific activity

-

specific activity

-

specific activity

63-85 nmol/min·mg

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

-

recombinant

expressed in baculovirus infected Sf9 cells

form

buffered aqueous glycerol solution

form

aqueous solution

form

buffered aqueous solution

form

buffered aqueous glycerol solution

mol wt

~38 kDa

mol wt

68 kDa

mol wt

94428 Da

mol wt

~67 kDa


pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1



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