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T9145

Thyroglobulin from bovine thyroid

(For Gel Filtration Chromatography)

Synonym(s):

Tg

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Size/SKUAvailabilityPrice
1 vial
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$150.00

About This Item

CAS Number:
UNSPSC Code:
12352202
EC Number:
232-721-3
NACRES:
NA.56
MDL number:
Form:
powder
Biological source:
bovine thyroid
Mol wt:
~670 kDa

$150.00


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biological source

bovine thyroid

Quality Segment

form

powder

mol wt

~670 kDa

technique(s)

bioconjugation: suitable

UniProt accession no.

storage temp.

−20°C

Gene Information

cow ... TG(280706)

Application

Often used as a carrier protein for the production of antibodies. Its advantage is the large number of tyrosine residues that can be used for conjugation using the diazo reaction.
Thyroglobulin is used for antibody purification and characterization. Thyroglobulin has been used in studies assessing the monitoring of differentiated thyroid cancer as well as to develop an accurate diagnostic tool for patients with autoimmune thyroid diseases.

Biochem/physiol Actions

Iodine-containing protein that is stored in the thyroid gland. Converted into circulating thyroxines when the thyroid is stimulated by thyroid-stimulating hormone (TSH) from the pituitary. Because its expression is unique to the thyroid, it is a sensitive indicator of recurrence or metastasis of thyroid cancer that has been treated by thyroid ablation.

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This Item
T1001609312T1126
description

(For Gel Filtration Chromatography)

description

powder, ≥90% (agarose gel electrophoresis)

description

-

description

powder

technique(s)

bioconjugation: suitable

technique(s)

-

technique(s)

-

technique(s)

protein purification: suitable

biological source

bovine thyroid

biological source

bovine thyroid

biological source

human thyroid

biological source

Porcine thyroid

mol wt

~670 kDa

mol wt

~670 kDa

mol wt

-

mol wt

~670 kDa

form

powder

form

powder

form

lyophilized

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

UniProt accession no.

P01267

UniProt accession no.

P01267

UniProt accession no.

-

UniProt accession no.

F1RRV3


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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



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Certificates of Analysis (COA)

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Questions

  1. Hello. Please, could you tell me the weight of powder in 1 vial of the product with catalog number T9145 (Thyroglobulin from bovine thyroid, 1VL). Thanks

    1 answer
    1. The vial content for this product is determined on a lot-specific basis and is reported on the Certificate of Analysis. The minimum protein content will be 35 mg/vial. A brief review of recent lots shows the average of 39 mg/vial. See the links below to review several recent Certificates:
      https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/T9145-1VL0000255415.pdf
      https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/T9145-1VL-KCSLCN3202.pdf
      https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/T9145-1VLSLCM4718.pdf

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