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T9777

Trypsin-chymotrypsin inhibitor

lyophilized powder

Synonym(s):

Bowman-Birk Inhibitor

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Size/SKUAvailabilityPrice
10 mg

Available to ship TODAYfromMILWAUKEE

$107.00
25 mg

Available to ship TODAYfromMILWAUKEE

$180.00
50 mg

Available to ship TODAYfromMILWAUKEE

$314.00
100 mg

Estimated to ship onOctober 01, 2026fromMILWAUKEE

$563.00
500 mg

Estimated to ship onOctober 01, 2026fromMILWAUKEE

$2,150.00

About This Item

CAS Number:
37330-34-0
UNSPSC Code:
12352202
NACRES:
NA.77
MDL number:
MFCD00132532

$107.00

Available to ship TODAYDetails

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Product Name

Trypsin-chymotrypsin inhibitor from Glycine max (soybean), lyophilized powder

biological source

Glycine max (soybean)

Quality Segment

form

lyophilized powder

composition

Protein, 70-90% biuret

storage temp.

2-8°C

General description

Highly cross-linked with seven disulfide bridges, Bowman-Birk inhibitor has spatially distinct domains for trypsin and chymotrypsin inhibition.
Trypsin-chymotrypsin inhibitor belongs to the family of plant protease inhibitors. It is mainly found in the legume (Fabaceae) and cereal (Poaceae) families. Trypsin-chymotrypsin inhibitor consists of many internal disulfide bonds between conserved Cys residues, which maintains structural stability and active conformation of the inhibitory loops. Trypsin-chymotrypsin has anticarcinogenic properties.

Application

Bowman Birk protease inhibitor prevents radiation-induced carcinogenesis by a reduction of incorrect DNA repairs, resulting in a reduced amount of dicentric chromosomes.
Trypsin-chymotrypsin inhibitor from Glycine max (soybean) has been used for flow cytometric separase activity assay. It has also been used to inhibit trypsin and chymotrypsin for in vitro gastrointestinal (GI) digestion studies.

Physical form

Lyophilized powder containing phosphate buffer salts, pH 7.6

Analysis Note

1 mg protein will inhibit ≥0.5 mg trypsin with activity of ~10,000 BAEE units per mg protein or ≥1.0 mg chymotrypsin with activity of ~40 BTEE units per mg protein.

Other Notes

One trypsin unit = ΔA253 of 0.001 per min with BAEE as substrate at pH 7.6 at 25 °C. Reaction volume = 3.2 mL (1 cm light path).
View more information on Trypsin Inhibitor.

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This Item
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Trypsin-chymotrypsin inhibitor from Glycine max (soybean) lyophilized powder

Sigma-Aldrich

T9777

Trypsin-chymotrypsin inhibitor from Glycine max (soybean)

Trypsin inhibitor from Glycine max (soybean) lyophilized powder

Sigma-Aldrich

T9003

Trypsin inhibitor from Glycine max (soybean)

Trypsin inhibitor from Glycine max (soybean) Isoelectric focusing marker, pI 4.6

Sigma-Aldrich

T1021

Trypsin inhibitor from Glycine max (soybean)

Trypsin inhibitor from Glycine max (soybean) lyophilized powder

Sigma-Aldrich

T9128

Trypsin inhibitor from Glycine max (soybean)

description

lyophilized powder

description

lyophilized powder

description

Isoelectric focusing marker, pI 4.6

description

lyophilized powder

biological source

Glycine max (soybean)

biological source

Glycine max (soybean)

biological source

Glycine max (soybean)

biological source

Glycine max (soybean)

Quality Level

200

Quality Level

300

Quality Level

200

Quality Level

300

form

lyophilized powder

form

lyophilized powder

form

powder

form

lyophilized powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

composition

Protein, 70-90% biuret

composition

-

composition

-

composition

-

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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