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V5765

Vascular Endothelial Growth Factor 165 human

≥95% (SDS-PAGE), recombinant, expressed in HEK 293 cells, lyophilized powder, suitable for cell culture

Synonyme(s) :

Vascular Endothelial Growth Factor 165

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À vous/RéférenceDisponibilitéPrix
10 μg
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302,00 €
50 μg
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1 030,00 €

A propos de cet article

UNSPSC Code:
12352202
NACRES:
NA.77
Biological source:
human
Recombinant:
expressed in HEK 293 cells
Assay:
≥95% (SDS-PAGE)
Form:
lyophilized powder
Mol wt:
dimer 42 kDa (glycosylated)
Impurities:
<0.075 EU/μg

302,00 €


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Nom du produit

VEGF165, recombinant, expressed in HEK 293 cells, suitable for cell culture

biological source

human

Quality Segment

recombinant

expressed in HEK 293 cells

description

Vascular Endothelial Growth Factor 165 human

assay

≥95% (SDS-PAGE)

form

lyophilized powder

potency

<10 ng/mL ED50

quality

endotoxin tested

mol wt

dimer 42 kDa (glycosylated)

packaging

pkg of 10 μg, pkg of 50 μg

technique(s)

cell culture | mammalian: suitable

impurities

<0.075 EU/μg

color

white

solubility

water: soluble

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... VEGFA(7422)

General description

VEGF165 is expressed in human HEK 293 cells as a glycosylated homodimer with an apparent molecular mass of 45 kDa. Production in human HEK 293 cells offers authentic glycosylation. Glycosylation contributes to stability in cell growth media and other applications.

Biochem/physiol Actions

VEGF165 belongs to the PDGF/VEGF growth factor family characterized by the presence of eight conserved cysteine residues and a cystine knot structure. VEGF is secreted by the majority of tumor cells and initiates angiogenesis by activating endothelial cells of existing blood vessels and promoting their migration.
VEGF has also been implicated in correlation with poor prognosis in breast cancer.
In addition, VEGF is released in rheumatoid arthritis in response to TNF-α, increasing endothelial permeability and stimulating angiogenesis (formation of capillaries).

Analysis Note

The specific activity was determined by the dose-dependent stimulation of the proliferation of HUVEC cells (human umbilical vein endothelial cells).

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description

recombinant, expressed in HEK 293 cells, suitable for cell culture

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description

NGF-β, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture

description

EPO, recombinant, expressed in HEK 293 cells, suitable for cell culture

biological source

human

biological source

human

biological source

human

biological source

human

assay

≥95% (SDS-PAGE)

assay

>95% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

recombinant

expressed in HEK 293 cells

recombinant

expressed in HEK 293 cells

recombinant

expressed in HEK 293 cells

recombinant

expressed in HEK 293 cells

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder


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Classe de stockage

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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