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V9505

Monoclonal Anti-Vitamin B12 antibody produced in mouse

clone CD-29, ascites fluid

Synonym(s):

Anti-Cyanocobalamin

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0.5 mL

Available to ship TODAYfromMILWAUKEE

$740.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
MFCD00164758
Conjugate:
unconjugated
Clone:
CD-29, monoclonal
Application:
ELISA (i)
Citations:
10

$740.00

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biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

CD-29, monoclonal

contains

15 mM sodium azide

technique(s)

indirect ELISA: 1:5,000

isotype

IgG1

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

General description

Monoclonal Anti-Vitamin B12 antibody reacts with vitamin B12, as well as with vitamin B12-KLH and vitamin B12-BSA conjugates in human plasma and serum.
Vitamin B12 or cobalamin is a water-soluble vitamin. It is the largest and most complex among all the vitamins. Vitamin B12 is naturally found in animal foods, meat, milk, egg, fish and shellfish.

Application

Monoclonal Anti-Vitamin (B12) antibody has been used in enzyme linked immunosorbent assay (ELISA)
Monoclonal Anti-Vitamin B12 antibody produced in mouse has also been used in immunocytochemistry.

Biochem/physiol Actions

Vitamin B12 serves as a cofactor for methionine synthase and L-methylmalonyl−coenzyme A mutase. It is essential for the maintenance and development of CNS. Vitamin B12 deficiency leads to megaloblastic anemia and neuropathy.
Vitamin B12 regulates genomic stability. While increased levels of vitamin B12 have been associated with hepatic and hematological disorders; cobalamin deficiency has been associated with orthostatic hypotension and depression . The antibody also detects coenzyme B12 and methyl vitamin B12, but does not associate with BSA, folic acid, and 5-methyltetrahyrofolic acid.
Vitamin B12 and folic acid can be used for treating disorders of central nervous system (CNS) development, mood, and cognitive decline, including some dementias.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Monoclonal Anti-Vitamin B12 antibody produced in mouse clone CD-29, ascites fluid

Sigma-Aldrich

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Sigma-Aldrich

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Monoclonal Anti-Fibronectin antibody produced in mouse

description

clone CD-29, ascites fluid

description

clone BM-23, ascites fluid

description

clone 85D4, ascites fluid

description

clone FN-15, ascites fluid

clone

CD-29, monoclonal

clone

BM-23, monoclonal

clone

85D4, monoclonal

clone

FN-15, monoclonal

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

antibody form

ascites fluid

antibody form

ascites fluid

antibody form

ascites fluid

antibody form

ascites fluid

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

technique(s)

indirect ELISA: 1:5,000

technique(s)

indirect ELISA: 1:4,000, immunoprecipitation (IP): suitable, capture ELISA: suitable, western blot: suitable

technique(s)

indirect ELISA: 1:8,000, western blot: suitable, dot blot: suitable

technique(s)

indirect immunofluorescence: 1:200 using cultured human fibroblasts, indirect ELISA: 1:5,000, microarray: suitable, western blot: 1:800

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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