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1457902

USP

Nefazodone hydrochloride

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl- 2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one hydrochloride, BMY-13754, MJ-13754-1, Serzone

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Pack SizeSKUAvailabilityPrice
200 mg
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$1,570.00

About This Item

Empirical Formula (Hill Notation):
C25H32ClN5O2 · HCl
CAS Number:
Molecular Weight:
506.47
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:

$1,570.00


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grade

pharmaceutical primary standard

API family

nefazodone

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

O=C1N(CCCN2CCN(C3=CC=CC(Cl)=C3)CC2)N=C(CC)N1CCOC4=CC=CC=C4.Cl

InChI

1S/C25H32ClN5O2.ClH/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22;/h3-6,8-11,20H,2,7,12-19H2,1H3;1H

InChI key

DYCKFEBIOUQECE-UHFFFAOYSA-N

Gene Information

Application

Nefazodone hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Nefazodone Hydrochloride Tablets

Biochem/physiol Actions

Novel antidepressant; mixed 5-HT2A serotonin receptor antagonist/serotonin uptake inhibitor.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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This Item
N553614579241673533
grade

pharmaceutical primary standard

grade

-

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

manufacturer/tradename

USP

manufacturer/tradename

-

manufacturer/tradename

USP

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

format

neat

format

-

format

neat

format

neat

API family

nefazodone

API family

-

API family

nefazodone

API family

trazodone

Gene Information

human ... HTR2A(3356), HTR2C(3358), SLC6A2(6530), SLC6A4(6532)

Gene Information

human ... HTR2A(3356), HTR2C(3358), SLC6A2(6530), SLC6A4(6532)

Gene Information

-

Gene Information

-


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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



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Electrochemical characterisation of nefazodone hydrochloride and voltammetric determination of the drug in pharmaceuticals and human serum.
Uslu, Bengi, and Sibel A. Ozkan.
Analytica Chimica Acta, 462.1, 49-57 (2002)
Anne-Charlotte Dubbelman et al.
Journal of chromatography. A, 1374, 122-133 (2014-12-02)
The present study investigated the practical use of modern ultra-high performance liquid chromatography (UHPLC) separation techniques for drug metabolite profiling, aiming to develop a widely applicable, high-throughput, easy-to-use chromatographic method, with a high chromatographic resolution to accommodate simultaneous qualitative and



Global Trade Item Number

SKUGTIN
1457902-200MG04061833852422

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