Key Documents

Spironolactone

Name: Spironolactone
Brand: USP
Price: 377 USD
Availability: InStock

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

4-Pregnen-21-oic acid-17α-ol-3-one-7α-thiol γ-lactone 7-acetate, 7α-(Acetylthio)-17α-hydroxy-3-oxopregn-4-ene-21-carboxylic acid γ-lactone

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Size/SKU	Availability	Price
125 mg	Check Cart for Availability	$377.00

About This Item

Empirical Formula (Hill Notation):

C₂₄H₃₂O₄S

CAS Number:

52-01-7

Molecular Weight:

416.57

NACRES:

NA.24

PubChem Substance ID:

329751140

UNSPSC Code:

41116107

MDL number:

MFCD00082250

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Properties

grade

pharmaceutical primary standard

agency

USP

API family

spironolactone

manufacturer/tradename

USP

mp

207-208 °C (lit.)

application(s)

pharmaceutical
pharmaceutical (small molecule)

format

neat

SMILES string

CC(=O)S[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CC[C@@]45CCC(=O)O5)[C@H]13

InChI

1S/C24H32O4S/c1-14(25)29-19-13-15-12-16(26)4-8-22(15,2)17-5-9-23(3)18(21(17)19)6-10-24(23)11-7-20(27)28-24/h12,17-19,21H,4-11,13H2,1-3H3/t17-,18-,19+,21+,22-,23-,24+/m0/s1

InChI key

LXMSZDCAJNLERA-ZHYRCANASA-N

Gene Information

human ... NR3C2(4306)

Description

General description

Find answers to frequently asked questions on USP products in USP FAQs.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Spironolactone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Spironolactone and Hydrochlorothiazide Compounded Oral Suspension
Spironolactone and Hydrochlorothiazide Tablets
Spironolactone Compounded Oral Suspension
Spironolactone Compounded Oral Suspension, Veterinary
Spironolactone Tablets

Biochem/physiol Actions

Spironolactone is a competitive aldosterone receptor antagonist. Used as potassium sparing diuretic.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

Compare Similar Items

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Show Differences

1 of 1

This Item	S1200000	PHR2886	BP306
USP 1619006 Spironolactone	S1200000 Spironolactone	Supelco PHR2886 Spironolactone	BP306 Spironolactone
description United States Pharmacopeia (USP) Reference Standard	description European Pharmacopoeia (EP) Reference Standard	description pharmaceutical secondary standard, certified reference material	description British Pharmacopoeia (BP) Reference Standard
manufacturer/tradename USP	manufacturer/tradename EDQM	manufacturer/tradename -	manufacturer/tradename BP
grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade pharmaceutical secondary standard, certified reference material	grade pharmaceutical primary standard
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical	application(s) pharmaceutical pharmaceutical small molecule
format neat	format neat	format -	format neat
agency USP	agency -	agency traceable to Ph. Eur. S1200000, USP 1619006	agency BP
mp 207-208 °C (lit.)	mp 207-208 °C (lit.)	mp 207-208 °C (lit.)	mp 207-208 °C (lit.)

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Pictograms

GHS08

Signal Word

Danger

Hazard Codes

H351,H360FD,H373

Precautionary Statements

P202 - P260 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Carc. 2 - Repr. 1B - STOT RE 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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Certificates of Analysis (COA)

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