05-636-AF488

Anti-phospho Histone H2A.X (Ser139), clone JBW301, Alexa Fluor^™ 488 Conjugate Antibody

Name: Anti-phospho Histone H2A.X (Ser139), clone JBW301, Alexa Fluor<SUP>™</SUP> 488 Conjugate Antibody
Brand: MM
Price: 583 EUR
Availability: InStock

clone JBW301, from mouse, ALEXA FLUOR^™ 488

Sinonimo/i:

Histone H2AX, H2a/x, Histone H2A.X

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Informazioni su questo articolo

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

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Nome del prodotto

Anti-phospho Histone H2A.X (Ser139), clone JBW301, Alexa Fluor^™ 488 Conjugate Antibody, clone JBW301, from mouse, ALEXA FLUOR^™ 488

biological source

mouse

conjugate

ALEXA FLUOR^™ 488

antibody form

purified antibody

antibody product type

primary antibodies

clone

JBW301, monoclonal

species reactivity

human

species reactivity (predicted by homology)

vertebrates (based on 100% sequence homology)

technique(s)

immunocytochemistry: suitable

isotype

IgG1

NCBI accession no.

NP_002096

UniProt accession no.

P16104

shipped in

wet ice

target post-translational modification

phosphorylation (pSer139)

Quality Level

100

Gene Information

human ... H2AX(3014)

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Questo articolo	05-636-AF647	05-636-AF555	05-636-I
Sigma-Aldrich 05-636-AF488 Anti-phospho Histone H2A.X (Ser139), clone JBW301, Alexa Fluor^™ 488 Conjugate Antibody	Sigma-Aldrich 05-636-AF647 Anti-phospho Histone H2A.X (Ser139) Antibody, clone JBW301, Alexa Fluor^™ 647	Sigma-Aldrich 05-636-AF555 Anticorpo anti-fosfo-H2A.X (Ser139), clone JBW301, coniugato con Alexa Fluor^™ 555	Sigma-Aldrich 05-636-I Anti-fosfo-istone H2A.X (Ser139), clone JBW301
clone JBW301, monoclonal	clone JBW301, monoclonal	clone JBW301, monoclonal	clone JBW301, monoclonal
biological source mouse	biological source mouse	biological source mouse	biological source mouse
conjugate ALEXA FLUOR^™ 488	conjugate ALEXA FLUOR^™ 647	conjugate ALEXA FLUOR^™ 555	conjugate -
antibody form purified antibody	antibody form purified antibody	antibody form purified antibody	antibody form purified immunoglobulin
species reactivity human	species reactivity human	species reactivity human	species reactivity human, rat, mouse
Gene Information human ... H2AX(3014)	Gene Information human ... H2AX(3014)	Gene Information human ... H2AX(3014)	Gene Information human ... H2AX(3014) mouse ... H2Ax(15270) rat ... H2Ax(500987)

Analysis Note

Evaluated by Immunocytochemistry in untreated (negative control) and Staurosporin treated HeLa cells.

Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected phospho-Histone H2A.X (Ser139) in Staurosporin treated HeLa cells, and not in untreated HeLa cells.

Application

This Anti-phospho Histone H2A.X (Ser139) antibody, clone JBW301, Alexa Fluor^™ 488 Conjugate is validated for use in ICC for the detection of phospho Histone H2A.X (Ser139).

General description

Histone H2A.X is a variant of histone H2A, and is similarly associated with genomic DNA. However, histone is structurally different from other members of the H2A family in possessing a C-terminal tail that contains the Ser139 residue that is phosphorylated in response to breaks in double-stranded DNA. The phosphorylation of H2A.X is a rapid process that is mediated by ATM/ATR proteins.

17 kDa calculated

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

ALEXA FLUOR is a trademark of Life Technologies

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Classe di stoccaggio

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Anti-phospho Histone H2A.X (Ser139), clone JBW301, Alexa Fluor™ 488 Conjugate Antibody

clone JBW301, from mouse, ALEXA FLUOR™ 488