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Merck

33-016

PI 3-Kinase HTRF® Assay; 384 wells

The PI 3-Kinase HTRF Assay is a high-performance assay kit that provides a universal method for testing all Class I PI3-Kinases in a homogeneous format. This pack size has a screening capacity of 1 plate.

Sinonimo/i:

Assay for PI 3-Kinase, HTRF Assay, PI 3-Kinase Assay

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Informazioni su questo articolo

Codice UNSPSC:
12161503
eCl@ss:
32161000
NACRES:
NA.84

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Livello qualitativo

100

Reattività contro le specie

human, mouse

Produttore/marchio commerciale

HTRF®
Upstate®

tecniche

activity assay: suitable (kinase)

N° accesso NCBI

NM_006218.2

N° accesso UniProt

P42336

Metodo di rivelazione

fluorometric (HTRF)

Condizioni di spedizione

dry ice

Informazioni sul gene

human ... PIK3CA(5290)

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Questo articolo
33-01733-03633-126
PI 3-Kinase HTRF® Assay; 384 wells The PI 3-Kinase HTRF Assay is a high-performance assay kit that provides a universal method for testing all Class I PI3-Kinases in a homogeneous format. This pack size has a screening capacity of 1 plate.

Sigma-Aldrich

33-016

PI 3-Kinase HTRF® Assay; 384 wells

PI 3-Kinase HTRF® Assay; 1920 wells The PI 3-Kinase HTRF Assay is a high-performance assay kit that provides a universal method for testing all Class I PI3-Kinases in a homogeneous format. This pack size has a screening capacity of 5 plates.

Sigma-Aldrich

33-017

PI 3-Kinase HTRF® Assay; 1920 wells

PI 3-Kinase HTRF® Assay; 10,000 wells The PI 3-Kinase HTRF Assay is a high-performance assay kit that provides a universal method for testing all Class I PI3-Kinases in a homogeneous format. This pack size has a screening capacity of 10,000 wells.

Sigma-Aldrich

33-036

PI 3-Kinase HTRF® Assay; 10,000 wells

PIP5-Kinase HTRF Assay The PIP5 Kinase HTRF Assay kit provides a method for assaying PI(4)P-5 kinases in a homogenous 1920 well format. Suitable for screening of potential inhibitors of these enzymes.

Sigma-Aldrich

33-126

PIP5-Kinase HTRF Assay

technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

species reactivity

human, mouse

species reactivity

mouse, human

species reactivity

mouse, human

species reactivity

human, mouse

manufacturer/tradename

HTRF®

manufacturer/tradename

HTRF®, Upstate®

manufacturer/tradename

HTRF®, Upstate®

manufacturer/tradename

HTRF®, Upstate®

NCBI accession no.

NM_006218.2

NCBI accession no.

NM_006218.2

NCBI accession no.

NM_006218.2

NCBI accession no.

NM_001135636.1, NM_001195733.1

UniProt accession no.

P42336

UniProt accession no.

P42336

UniProt accession no.

P42336

UniProt accession no.

-

detection method

fluorometric (HTRF)

detection method

fluorometric (HTRF)

detection method

fluorometric (HTRF)

detection method

fluorometric (HTRF)

Applicazioni

Used to detect/quantify: PI 3-Kinase

Azioni biochim/fisiol

Target Sub-Family: PI3K/PI4K

Confezionamento

Kit capacity: 384 wells

Altre note

4X Reaction Buffer

PIP2 (Substrate; 1mM stock)

Stop Reagent A

Stop Reagent B

DM A Detection Reagent

DM B Detection Reagent

DM C Detection Reagent

Note legali

HTRF is a registered trademark of Cis Bio International
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H319

Classi di pericolo

Eye Irrit. 2

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Stephen Jamieson et al.
The Biochemical journal, 438(1), 53-62 (2011-06-15)
Genetic alterations in PI3K (phosphoinositide 3-kinase) signalling are common in cancer and include deletions in PTEN (phosphatase and tensin homologue deleted on chromosome 10), amplifications of PIK3CA and mutations in two distinct regions of the PIK3CA gene. This suggests drugs
James M J Dickson et al.
Bioscience reports, 33(6) (2013-08-24)
NTT (N-terminal tags) on the catalytic (p110) sub-unit of PI 3-K (phosphoinositol 3-kinase) have previously been shown to increase cell signalling and oncogenic transformation. Here we test the impact of an NT (N-terminal) His-tag on in vitro lipid and protein
Christina M Buchanan et al.
PloS one, 8(8), e71337-e71337 (2013-08-13)
In addition to lipid kinase activity, the class-I PI 3-kinases also function as protein kinases targeting regulatory autophosphorylation sites and exogenous substrates. The latter include a recently identified regulatory phosphorylation of the GM-CSF/IL-3 βc receptor contributing to survival of acute
Qin Li et al.
Toxicology research, 8(3), 353-360 (2019-06-05)
Qingkailing injection (QKLI) is a kind of multi-component traditional Chinese medicine injection. It has been widely used in clinical practice, but in recent years, it has caused more and more adverse reactions, mainly manifested as pseudo-allergic symptoms. To explore the

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