Mebendazole

Name: Mebendazole
Brand: SIAL
Price: 111 EUR

VETRANAL^®, analytical standard

Sinonimo/i:

5-Benzoyl-2-benzimidazolecarbamic acid methyl ester, Mebendazol, Methyl N-(5-benzoyl-1H-benzimidazol-2-yl)carbamate

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250 MG

111,00 €

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Informazioni su questo articolo

Formula empirica (notazione di Hill):

C₁₆H₁₃N₃O₃

Numero CAS:

31431-39-7

Peso molecolare:

295.29

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329757164

EC Number:

250-635-4

Beilstein/REAXYS Number:

759809

MDL number:

MFCD00057872

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Nome del prodotto

Mebendazole, VETRANAL^®, analytical standard

InChI key

OPXLLQIJSORQAM-UHFFFAOYSA-N

InChI

1S/C16H13N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,17,18,19,21)

SMILES string

COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c3ccccc3

grade

analytical standard

product line

VETRANAL^®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

Quality Level

100

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Questo articolo	PHR2448	M0215000	BP1008
Supelco 46404 Mebendazole	Supelco PHR2448 Mebendazole	M0215000 Mebendazole	BP1008 Mebendazole
application(s) clinical testing	application(s) pharmaceutical small molecule	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical pharmaceutical small molecule
technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) -	technique(s) -	technique(s) -
format neat	format -	format neat	format neat
Quality Level 100	Quality Level 300	Quality Level -	Quality Level -
grade analytical standard	grade certified reference material, pharmaceutical secondary standard	grade pharmaceutical primary standard	grade pharmaceutical primary standard
shelf life limited shelf life, expiry date on the label	shelf life -	shelf life -	shelf life limited shelf life, expiry date on the label

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number

BCCG4824

BCCD7494

BCBR9633V

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Repositioning of the anthelmintic drug mebendazole for the treatment for colon cancer.

Peter Nygren et al.

Journal of cancer research and clinical oncology, 139(12), 2133-2140 (2013-10-19)

In the present study, we screened a compound library containing 1,600 clinically used compounds with the aim to identify compounds, which potentially could be repositioned for colon cancer therapy. Two established colon cancer cell lines were tested using the fluorometric

Predicting new indications for approved drugs using a proteochemometric method.

Sivanesan Dakshanamurthy et al.

Journal of medicinal chemistry, 55(15), 6832-6848 (2012-07-12)

The most effective way to move from target identification to the clinic is to identify already approved drugs with the potential for activating or inhibiting unintended targets (repurposing or repositioning). This is usually achieved by high throughput chemical screening, transcriptome

In vivo dog intestinal precipitation of mebendazole: a basic BCS class II drug.

Sara Carlert et al.

Molecular pharmaceutics, 9(10), 2903-2911 (2012-09-08)

The purpose of this study was to investigate in vivo intestinal precipitation of a model drug mebendazole, a basic BCS class II drug, using dogs with intestinal stomas for administration or sampling. After oral administration of a solution with an

Effects of the benzimidazole anthelmintic drug flubendazole on rat embryos in vitro.

Monica Longo et al.

Reproductive toxicology (Elmsford, N.Y.), 36, 78-87 (2013-01-05)

Filarial diseases affect millions of people in poverty-stricken areas. In 2011, an investigation of the potential of flubendazole as a safe, highly efficacious, and field-usable macrofilaricidal drug was begun by Drug for Neglected Diseases initiative. As part of the preclinical

Mebendazole and related anthelmintics.

H Van den Bossche et al.

Advances in pharmacology and chemotherapy, 19, 67-128 (1982-01-01)

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