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Merck

58756

1-(5-Isoquinolinesulfonyl)-3-methylpiperazine

≥98.0% (HPLC)

Sinonimo/i:

1-(5-Isoquinolinylsulfonyl)-3-methylpiperazine, Iso-H-7

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5 MG

92,90 €

92,90 €

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Informazioni su questo articolo

Formula empirica (notazione di Hill):
C14H17N3O2S
Numero CAS:
84477-73-6
Peso molecolare:
291.37
UNSPSC Code:
12352202
NACRES:
NA.77
PubChem Substance ID:
57651659
MDL number:
MFCD00132900
Beilstein/REAXYS Number:
5445506

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Nome del prodotto

1-(5-Isoquinolinesulfonyl)-3-methylpiperazine, ≥98.0% (HPLC)

InChI

1S/C14H17N3O2S/c1-11-10-17(8-7-16-11)20(18,19)14-4-2-3-12-9-15-6-5-13(12)14/h2-6,9,11,16H,7-8,10H2,1H3

SMILES string

CC1CN(CCN1)S(=O)(=O)c2cccc3cnccc23

InChI key

QGSCXAWTTISKLF-UHFFFAOYSA-N

assay

≥98.0% (HPLC)

form

powder

storage temp.

2-8°C

Quality Level

100

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Categorie correlate

Biochem/physiol Actions

Less potent inhibitor of protein kinaseC than H-7

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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J Duraj et al.
Neoplasma, 44(4), 205-211 (1997-01-01)
The human pre-B acute lymphoblastic leukemia cell line REH6 was utilized for characterization of CD45 glycoprotein by monoclonal antibodies (mAb) recognizing four distinct CD45 antigen specificities, i.e. nonrestricted CD45, restricted CD45RA, CD45RB and CD45R0. Immunoprecipitation revealed two antigen specificities on
C C Chua et al.
Biochimica et biophysica acta, 1401(2), 187-194 (1998-04-09)
Vascular endothelial growth factor (VEGF) is a potent mitogen for endothelial cells and a vascular permeability factor. In this study we found that the addition of angiotensin II (AII) to rat heart endothelial cells induced VEGF mRNA production. VEGF mRNA
C D Balaban et al.
Brain research, 845(1), 97-101 (1999-10-26)
This study tests the hypothesis that activation of protein kinase C (PKC) is a critical step for early recovery from spontaneous nystagmus after unilateral ablation of the vestibular periphery. Halothane-NO(2)-O(2)-anesthetized Long-Evans rats received a 5-microl intracerebroventricular bolus of vehicle (distilled
H Takahashi et al.
Biological & pharmaceutical bulletin, 20(4), 446-448 (1997-04-01)
Capric acid (C10) enhanced the absorption of cefoxitin sodium in a concentration-dependent manner following the rectal administration as a suppository in rats. The optimal concentration of C10 was 13%. C10 administered as a suppository also reduced rectal membrane resistance (Rm)
A Broberg et al.
Biochemical and biophysical research communications, 280(1), 328-333 (2001-02-13)
Integrin alpha1beta1, one of the cellular collagen receptors, can participate in the regulation of collagen accumulation by acting as a negative feedback regulator. The molecular mechanism behind this phenomenon has been unknown. We have plated cells inside three-dimensional collagen and
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