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Merck

61962

Betaine

BioUltra, ≥99.0% (NT)

Sinonimo/i:

(Carboxymethyl)trimethylammonium inner salt, Oxyneurine, Trimethylglycine

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50 G

50,20 €

250 G

209,00 €

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Informazioni su questo articolo

Formula condensata:
(CH3)3N+CH2COO-
Numero CAS:
Peso molecolare:
117.15
Beilstein:
3537113
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.25

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Nome Commerciale

BioUltra

Saggio

≥99.0% (NT)

Impurezze

insoluble matters, passes filter test

Solubilità

methanol: 1 M at 20 °C, clear, colorless

Anioni in tracce

chloride (Cl-): ≤200 mg/kg
sulfate (SO42-): ≤200 mg/kg

Cationi in tracce

Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤100 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

Assorbimento

≤0.05 at 280 nm in methanol at 1 M
≤0.09 at 260 nm in methanol at 1 M

Stringa SMILE

C[N+](C)(C)CC([O-])=O

InChI

1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3
KWIUHFFTVRNATP-UHFFFAOYSA-N

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Questo articolo
W422312B0300B2629
Betaine BioUltra, ≥99.0% (NT)

Sigma-Aldrich

61962

Betaine

Betaine ≥98%

Sigma-Aldrich

W422312

Betaine

Betaina 5 M, PCR Reagent

Sigma-Aldrich

B0300

Betaina

Betaine ≥98% (perchloric acid titration)

Sigma-Aldrich

B2629

Betaine

impurities

insoluble matters, passes filter test

impurities

-

impurities

-

impurities

-

assay

≥99.0% (NT)

assay

≥98%

assay

-

assay

≥98% (perchloric acid titration)

product line

BioUltra

product line

-

product line

-

product line

-

solubility

methanol: 1 M at 20 °C, clear, colorless

solubility

-

solubility

-

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

anion traces

chloride (Cl-): ≤200 mg/kg

anion traces

-

anion traces

-

anion traces

-

cation traces

Ca: ≤10 mg/kg

cation traces

-

cation traces

-

cation traces

-

Descrizione generale

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

Applicazioni

Betaine has been used in reverse transcription to increase the thermal stability of proteins and to destabilize the DNA helix.[1]

Azioni biochim/fisiol

Betaine has been shown to increase S-adenosylmethionine (SAM) levels and hence, may have a role in diminishing hepatic steatosis. It is an osmolyte which protects cells against environmental stress.[2][3]
End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.[4]

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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The apicomplexans are a group of obligate animal pathogens that include Plasmodium (malaria), Toxoplasma (toxoplasmosis), and Cryptosporidium (cryptosporidiosis) [1]. They are an extremely diverse and specious group but are nevertheless united by a distinctive suite of cytoskeletal and secretory structures related to
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Following implantation, the epiblast (EPI) cells transit from the naive to primed pluripotency, accompanied by dynamic changes in X chromosome activity in females. To investigate the molecular attributes of this process, we performed single-cell RNA-seq analysis of 1,724 cells of
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Current drug metabolism, 6(1), 15-22 (2005-02-22)
High plasma concentrations of homocysteine may increase risk of cardiovascular disease. Folic acid lowers plasma homocysteine by 25% maximally, because 5-methyltetrahydrofolate is a methyl donor in the remethylation of homocysteine to methionine. Betaine (trimethylglycine) is also a methyl donor in
M F Abdelmalek et al.
The American journal of gastroenterology, 96(9), 2711-2717 (2001-09-25)
No effective therapy currently exists for patients with nonalcoholic steatohepatitis (NASH). Betaine, a naturally occurring metabolite of choline, has been shown to raise S-adenosylmethionine (SAM) levels that may in turn play a role in decreasing hepatic steatosis. Our aim was

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