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Merck

C6277

Congo Red

Dye content, ≥85%, certified by the Biological Stain Commission, powder

Sinonimo/i:

Congo Red 4B, Cosmos Red, Cotton Red B, Cotton Red C, Direct Red 28, Direct Red R, Direct Red Y

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25 G

350,00 €

350,00 €


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Informazioni su questo articolo

Formula empirica (notazione di Hill):
C32H22N6Na2O6S2
Numero CAS:
Peso molecolare:
696.66
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
209-358-4
MDL number:
Colour Index Number:
22120
Beilstein/REAXYS Number:
3894858

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Nome del prodotto

Congo Red, certified by the BSC, BioXtra

InChI key

IQFVPQOLBLOTPF-HKXUKFGYSA-L

InChI

1S/C32H24N6O6S2.2Na/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34;;/h1-18H,33-34H2,(H,39,40,41)(H,42,43,44);;/q;2*+1/p-2/b37-35+,38-36+;;

SMILES string

[Na+].[Na+].Nc1c(cc(c2ccccc12)S([O-])(=O)=O)\N=N\c3ccc(cc3)-c4ccc(cc4)\N=N\c5cc(c6ccccc6c5N)S([O-])(=O)=O

agency

certified by the BSC

product line

BioXtra

form

powder

composition

Dye content, ≥85%

technique(s)

microbe id | staining: suitable

mp

>360 °C (lit.)

solubility

H2O: 10 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

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Questo articolo
C6767S4261S4136
Congo Red certified by the BSC, BioXtra

Sigma-Aldrich

C6277

Congo Red

Congo Red Dye content ≥35 %

Sigma-Aldrich

C6767

Congo Red

Sudan IV certified by the BSC, BioXtra

Sigma-Aldrich

S4261

Sudan IV

Sudan III BioXtra, certified by the BSC

Sigma-Aldrich

S4136

Sudan III

grade

certified by the Biological Stain Commission

grade

-

grade

certified by the Biological Stain Commission

grade

certified by the Biological Stain Commission

technique(s)

microbe id | staining: suitable

technique(s)

titration: suitable

technique(s)

-

technique(s)

-

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

form

powder

form

powder

form

powder

form

powder

solubility

H2O: 10 mg/mL

solubility

H2O: 1 mg/mL

solubility

-

solubility

toluene: 1 mg/mL, clear, red

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

Application

Certified for use as a counterstain for alum based hematoxylin and in the Highman or the Churukian modification of Puchtler′s amyloid stain.
Congo red has been used for the staining of β amyloid peptides.[1][2][3]

Biochem/physiol Actions

Congo red is a benzidine-based anionic diazo dye.[4] It is a histological dye which binds to many amyloid proteins and is used for the quantification of amyloid β-peptide aggregation.[5] Congo red also interacts with β-D-glucans, polysaccharides containing continuous β-(1→4)-linked D-glucopyranosyl units and some hemicellulosic galactoglucomannans.[6]

pictograms

Health hazard

signalword

Danger

Hazard Classifications

Carc. 1B - Repr. 2

Classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


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Efficient imaging of amyloid deposits in Drosophila models of human amyloidoses.
Berg I, et al.
Nature Protocols, 5, 935-935 (2010)
Long-term treatment of thalidomide ameliorates amyloid-like pathology through inhibition of ?-secretase in a mouse model of Alzheimer's disease.
He P, et al.
PLoS ONE, 8, e55091-e55091 (2013)
Alejandro Llanos-Chea et al.
Journal of pediatric gastroenterology and nutrition, 68(4), 509-516 (2018-11-13)
Enteric bacterial pathogens cause diarrheal disease and mortality at significant rates throughout the world, particularly in children younger than 5 years. Our ability to combat bacterial pathogens has been hindered by antibiotic resistance, a lack of effective vaccines, and accurate
Kinetic study and equilibrium isotherm analysis of Congo Red adsorption by clay materials.
Vimonses V, et al.
Chemical Engineering Journal, 148, 354-364 (2009)
Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3.
Sanan DA, et al.
The Journal of Clinical Investigation, 94, 860-860 (1994)

Domande

1–3 di 3 domande  
  1. looking for Congo Red stain, the one used in histopathology, but not sure which of the options is the best.

    1 risposta
    1. The dry powder form allows for the preparation of Congo Red for various uses. The recommended dry dye for ordering is C6277 is currently undergoing BSC certification. Congo Red is a dye used for various staining procedures, mostly for staining of amyloid.

      Utile?

  2. Why does the SDS for Congo Red list carcinogen as an OSHA hazard, (Section 2) but in Section 11 on carcinogenicity, it states that there is no component identified as a carcinogen?

    1 risposta
    1. The reason that there is not an OSHA listing for carcinogens on most of SDS that have a hazard of a carcinogen hazard is because that section of the SDS is specifically for the OSHA regulated carcinogens, also referred to as the OSHA 13. Congo red at this time is not specifically called out  as a carcinogen by the other 3 Organizations listed (IARC, NTP, ACGIH) either. Congo red is listed by the European Classification Labeling & Packaging (CLP) Regulation (which is a pretty definitive guide for hazard classification), as a carcinogen. No other organizations have had the time to classify this material at this time. This is why it is only listed as a carcinogen in section 2 and in section 15.

      Utile?

  3. What is the Department of Transportation shipping information for this product?

    1 risposta
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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