M7008

4-Methylumbelliferyl-β-D-xylopyranoside

Name: 4-Methylumbelliferyl-β-<SC>D</SC>-xylopyranoside
Brand: SIGMA
Price: 97.6 EUR

β-xylosidase substrate, fluorogenic, ≥98% (HPLC), powder

Sinonimo/i:

4-Methylumbelliferyl β-D-xyloside

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25 MG

97,60 €

100 MG

260,00 €

250 MG

496,00 €

1 G

1.690,00 €

97,60 €

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Informazioni su questo articolo

Formula empirica (notazione di Hill):

C₁₅H₁₆O₇

Numero CAS:

6734-33-4

Peso molecolare:

308.28

NACRES:

NA.32

PubChem Substance ID:

24897133

UNSPSC Code:

12352204

EC Number:

229-784-4

MDL number:

MFCD00037607

Beilstein/REAXYS Number:

39934

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Nome del prodotto

4-Methylumbelliferyl-β-D-xylopyranoside, β-xylosidase substrate

InChI key

JWIYLOHVJDJZOQ-KAOXEZKKSA-N

InChI

1S/C15H16O7/c1-7-4-12(17)22-11-5-8(2-3-9(7)11)21-15-14(19)13(18)10(16)6-20-15/h2-5,10,13-16,18-19H,6H2,1H3/t10-,13+,14-,15+/m1/s1

SMILES string

CC1=CC(=O)Oc2cc(O[C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)ccc12

assay

≥98% (HPLC)

form

powder

solubility

pyridine: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

Quality Level

200

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Questo articolo	M9659	M0905	M3657
Sigma-Aldrich M7008 4-Methylumbelliferyl-β-D-xylopyranoside	Sigma-Aldrich M9659 4-Methylumbelliferyl N-acetyl-β-D-galactosaminide	Sigma-Aldrich M0905 4-Methylumbelliferyl β-D-mannopyranoside	Sigma-Aldrich M3657 4-Methylumbelliferyl α-D-mannopyranoside
assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (TLC)	assay ≥97% (HPLC)
solubility pyridine: 50 mg/mL, clear, colorless to faintly yellow	solubility pyridine: 50 mg/mL, clear, colorless to faintly yellow	solubility pyridine: 10 mg/mL, clear, colorless to faintly yellow	solubility pyridine: 20 mg/mL, clear, colorless to faintly yellow
Quality Level 200	Quality Level 200	Quality Level 300	Quality Level 300
form powder	form powder	form powder	form powder
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C

General description

A substrate for β-xylosidase

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Alterations of matrix- and cell-associated proteoglycans inhibit osteogenesis and growth response to fibroblast growth factor-2 in cultured rat mandibular condyle and calvaria.

A Molténi et al.

Cell and tissue research, 295(3), 523-536 (1999-02-18)

Matrix and cell surface proteoglycans (PGs) may play important roles in the control of cellular actions of heparan-binding growth factors such as fibroblast growth factor (FGF) during chondrogenesis and osteogenesis. In this study, we used 4-methylumbelliferyl-beta-d-xyloside, an inhibitor of PG

Regulation of heparan sulfate and chondroitin sulfate glycosaminoglycan biosynthesis by 4-fluoro-glucosamine in murine airway smooth muscle cells.

Julie Nigro et al.

The Journal of biological chemistry, 284(25), 16832-16839 (2009-04-07)

The importance of the pathological changes in proteoglycans has driven the need to study and design novel chemical tools to control proteoglycan synthesis. Accordingly, we tested the fluorinated analogue of glucosamine (4-fluoro-N-acetyl-glucosamine (4-F-GlcNAc)) on the synthesis of heparan sulfate (HS)

Characterization of beta-D-xyloside-induced glycosaminoglycans and oligosaccharides in cultured human skin fibroblasts.

K Takagaki et al.

Journal of biochemistry, 109(4), 514-519 (1991-04-01)

Human skin fibroblasts were incubated in the presence of a fluorogenic xyloside, 4-methylumbelliferyl beta-D-xyloside. Three fluorogenic components were isolated and purified from the culture medium by gel permeation high-performance liquid chromatography. Their structures were then characterized by enzymatic digestion, fast-atom-bombardment

A novel oligosaccharide, GlcA beta 1-4Xyl beta 1-(4-methylumbelliferone), synthesized by human cultured skin fibroblasts.

T Nakamura et al.

The Biochemical journal, 304 ( Pt 3), 731-736 (1994-12-15)

Human skin fibroblasts were cultured in the presence of 4-methylumbelliferyl-beta-D-xyloside (Xyl-MU) using a mass-culture system with a microcarrier. The structures of Xyl-MU-induced sugars purified from the dialysable fraction of the incubation medium were investigated. In addition to glycosaminoglycans the elongation

Characterization and biological significance of sialyl alpha 2-3galactosyl beta 1-4xylosyl beta 1-(4-methylumbelliferone) synthesized in cultured human skin fibroblasts.

K Takagaki et al.

Journal of biochemistry, 119(4), 697-702 (1996-04-01)

Human skin fibroblasts were incubated in the presence of a fluorogenic xyloside, 4-methyl-umbelliferyl-beta-D-xyloside (Xyl-MU), then the cultured medium was recovered, concentrated with a lyophilizer, and dialyzed against distilled water. The structures of the Xyl-MU derivatives purified from the dialyzable fraction

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4-Methylumbelliferyl-β-D-xylopyranoside