O8010

Okadaic acid ammonium salt

From plant (Prorocentrum concavum), ≥90% (HPLC), type 1 and type 2A protein phosphatases inhibitor, solid

• Sinonimo/i: OA
• Formula empirica (notazione di Hill): C₄₄H₆₈O₁₃ · NH₃
• Numero CAS: 155716-06-6
• Peso molecolare: 822.03
• UNSPSC Code: 12352106
• PubChem Substance ID: 24898053
• NACRES: NA.77
• MDL number: MFCD00153856

Proprietà

• Nome del prodotto: Okadaic acid ammonium salt from Prorocentrum concavum, ≥90% (HPLC), solid
• SMILES string: [H][N+]([H])([H])[H].[H][C@]1(CC[C@@H](O)[C@@]2(O[C@@H](CC(C)=C2)C(C)\C=C\[C@@]3([H])CC[C@@]4(CCC5O[C@H]([C@@H](O)C[C@H](C)C6O[C@@]7(CCCCO7)CC[C@H]6C)C(=C)[C@@H](O)[C@]5([H])O4)O3)O1)C[C@@](C)(O)C([O-])=O
• InChI key: ZBOMSHVRJSJGNR-JBNKPAQWSA-N
• InChI: 1S/C44H68O13.H3N/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42;/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49);1H3/b10-9+;/t26-,27-,28+,30+,31+,32+,33?,34+,35-,36-,37?,38+,39-,41-,42+,43-,44-;/m1./s1
• biological source: plant (Prorocentrum concavum)
• assay: ≥90% (HPLC)
• form: solid
• color: white
• solubility: H₂O: 0.1 mg/mL; DMSO: soluble; ethanol: soluble
• storage temp.: −20°C
• Quality Level: 200

Descrizione

Biochem/physiol Actions

Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases. Does not inhibit tyrosine phosphatases, alkaline phosphatases or acid phosphatase. Known tumor promotor. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling.

Okadaic acid is a dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid.

Informazioni sulla sicurezza

• pictograms: GHS06
• signalword: Danger
• hcodes: H301 + H311 + H331,H315
• pcodes: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Skin Irrit. 2
• Classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3