SAB6012079

Anti Growth differentiation factor 3 Antibody, clone 23GB5540, Rabbit Monoclonal

clone 23GB5540, recombinant rabbit monoclonal, expressed in HEK293 cells

• Sinonimo/i: GDF-3, KFS3, MCOP7
• Codice UNSPSC: 12352203

Proprietà

• Origine biologica: rabbit (Monoclonal)
• Livello qualitativo: 100
• Ricombinante: expressed in HEK 293 cells
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: 23GB5540, recombinant monoclonal
• Stato: buffered aqueous glycerol solution
• PM: 41 kDa
• Reattività contro le specie: human, rat
• Confezionamento: vial of 1.5 mL
• Convalida avanzata: recombinant expression; Learn more about Antibody Enhanced Validation
• sustainability: Greener Alternative Product
• Concentrazione: 1.3 mg/ml
• tecniche: western blot: 1:1,000-1:5,000
• Isotipo: IgG
• N° accesso Ensembl | uomo: ENSG00000184344
• N° accesso NCBI: NP_065685.1
• N° accesso UniProt: Q9NR23
• Categoria alternativa più verde: DfS-Developed
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... GDF3(9573)

Descrizione

Descrizione generale

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016]

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Immunogeno

A synthesized peptide corresponding to a sequence within amino acids 300-364 of human GDF3 [NP_065685.1].

Stato fisico

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

Altre note

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.