MAB1276

Anti-Nuclei & Chromosomes Antibody, histone H1 protein, clone 1415-1

Name: Anti-Nuclei & Chromosomes Antibody, histone H1 protein, clone 1415-1
Brand: MM

clone 1415-1, Chemicon^®, from mouse

別名:

Anti-H1.4, Anti-H1E, Anti-H1F4, Anti-H1s-4, Anti-HIST1H1E, Anti-RMNS, Anti-dJ221C16.5

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この製品は、Merck Milliporeウェブサイトでのみ注文できます。

この商品について

UNSPSCコード:

12352203

eCl@ss:

32160702

NACRES:

NA.41

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由来生物

mouse

品質水準

100

結合体

unconjugated

抗体製品の状態

purified antibody

抗体製品タイプ

primary antibodies

クローン

1415-1, monoclonal

交差性

human, rat

メーカー／製品名

Chemicon^®

テクニック

ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable

アイソタイプ

IgG2a

NCBIアクセッション番号

NM_005321.2

UniProtアクセッション番号

P10412

輸送温度

wet ice

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... H1-1(3024)

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当該品目	MAB3864	H7789	MABE71
Sigma-Aldrich MAB1276 Anti-Nuclei & Chromosomes Antibody, histone H1 protein, clone 1415-1	Sigma-Aldrich MAB3864 抗DNA/ヒストンH1抗体	Sigma-Aldrich H7789 抗アセチル-ヒストンH1.4 (Ac-Lys²⁶) ウサギ宿主抗体	Sigma-Aldrich MABE71 Anti-Histone Antibody, Pan, clone F152.C25.WJJ
species reactivity human, rat	species reactivity -	species reactivity human	species reactivity human, bovine
biological source mouse	biological source mouse	biological source rabbit	biological source mouse
Gene Information human ... H1-1(3024)	Gene Information human ... H1-1(3024)	Gene Information human ... HIST1H1E(3008)	Gene Information human ... H2AC21(317772)
antibody form purified antibody	antibody form purified antibody	antibody form affinity isolated antibody	antibody form purified immunoglobulin
clone 1415-1, monoclonal	clone monoclonal	clone polyclonal	clone F152C25W, monoclonal
shipped in wet ice	shipped in wet ice	shipped in dry ice	shipped in wet ice

免疫原

Epitope: histone H1 protein

アプリケーション

Anti-Nuclei & Chromosomes, histone H1 protein, clone 1415-1 is a high quality Mouse Monoclonal Antibody for the detection of Nuclei & Chromosomes & has been validated in ELISA, WB, ICC, IHC(P).

生物化学的／生理学的作用

Histone specific; stains nuclei and chromosomes of cells of all species including animals and plants. Reacts with preferentially with Histone H1 by ELISA and immunoblotting. MAB1276 produces a speckled nuclear staining pattern in all tissues studies.

Stains nuclei of all human cell types and also stains chromosomes diffusely in metaphase cells. Nuclear staining in interphase cells is intense and diffuse. Antibody reacts with rat cells {Bendeck, 2001}.

物理的形状

100 μL Hybridoma Supernatant, concentrated by ammonium sulfate. Buffer: PBS with 0.1% sodium azide.

Format: Purified

アナリシスノート

Control
POSITIVE CONTROL:

Human tonsil

法的情報

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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保管分類コード

12 - Non Combustible Liquids

WGK

WGK 2

引火点(°F)

Not applicable

引火点(℃)

Not applicable

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

MAB1276:

試験成績書（COA）

製品のロット番号・バッチ番号を入力して、試験成績書（COA）を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

The beta3 integrin antagonist m7E3 reduces matrix metalloproteinase activity and smooth muscle cell migration.

M P Bendeck et al.

Journal of vascular research, 38(6), 590-599 (2001-12-12)

Treatment with c7E3 (abciximab, ReoPro) has been associated with a reduction in coronary events and the need for revascularization. Some of these beneficial effects may be due to blockade of the alphavbeta3 integrin receptor on smooth muscle cells (SMCs), however

In vivo effect of insulin to decrease matrix metalloproteinase-2 and -9 activity after arterial injury.

June Guo et al.

Journal of vascular research, 50(4), 279-288 (2013-08-31)

In vitro, insulin has both growth-promoting and vasculoprotective effects. In vivo, the effect of insulin is mainly protective. Insulin treatment (3 U/day) decreases smooth muscle cell (SMC) migration and neointimal growth after carotid angioplasty in normal rats maintained at normoglycemia

Human umbilical cord blood mononuclear cells and chorionic plate-derived mesenchymal stem cells promote axon survival in a rat model of optic nerve crush injury.

Sokjoong Chung et al.

International journal of molecular medicine, 37(5), 1170-1180 (2016-03-18)

The use of mesenchymal stem cells (MSCs) in cell therapy in regenerative medicine has great potential, particularly in the treatment of nerve injury. Umbilical cord blood (UCB) reportedly contains stem cells, which have been widely used as a hematopoietic source

An essential role for gp130 in neointima formation following arterial injury.

Dong Wang et al.

Circulation research, 100(6), 807-816 (2007-02-27)

Interleukin (IL)-6 induced vascular smooth muscle cell (VSMC) motility in a dose-dependent manner. In addition, IL-6 stimulated tyrosine phosphorylation of gp130, resulting in the recruitment and activation of STAT-3. IL-6-induced VSMC motility was found to be dependent on activation of

The aurora B kinase AIR-2 regulates kinetochores during mitosis and is required for separation of homologous Chromosomes during meiosis.

Susanne Kaitna et al.

Current biology : CB, 12(10), 798-812 (2002-05-17)

Mitotic chromosome segregation depends on bi-orientation and capture of sister kinetochores by microtubules emanating from opposite spindle poles and the near synchronous loss of sister chromatid cohesion. During meiosis I, in contrast, sister kinetochores orient to the same pole, and

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