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Merck

S1-M

Human Serum, Normal

別名:

Normal Human Serum

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この商品について

UNSPSCコード:
41105901
eCl@ss:
26020100
NACRES:
NA.71

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由来生物

human

抗体製品の状態

serum

メーカー/製品名

Chemicon®

テクニック

blocking: suitable (interfering antibodies)

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当該品目
NS03L869019-MNS01L
biological source

human

biological source

mouse

biological source

-

biological source

rabbit

technique(s)

blocking: suitable (interfering antibodies)

technique(s)

-

technique(s)

-

technique(s)

-

manufacturer/tradename

Chemicon®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

antibody form

serum

antibody form

-

antibody form

-

antibody form

-

詳細

Normal human serum collected off the clot from healthy normal humans. Each donor unit was tested and found negative for HIV 1&2, HIV-Ag, HCV, HBsAg, and RPR by FDA approved methods.

アプリケーション

Normal Human Serum has been used as a reference or control in degradation assays involving DNase I and MNase treatments, providing a comparison for assessing the impact of these enzymes on the DHM structures.[1]

物理的形状

Nonsterile liquid. Contains no preservatives.

Filtered through a 0.2μ absolute membrane filter before bottling.

調製ノート

Store frozen at -20°C for up to 12 months. Avoid repeated freeze/thaw cycles.

法的情報

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

保管分類コード

10 - Combustible liquids

WGK

WGK 1

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

S1-100ML:
S1-LITER:
S1-100-KC:


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Midori L Wasielewski et al.
International journal of molecular sciences, 24(4) (2023-02-26)
This study analyzed the nuclease- and serum-driven degradation of millimeter-scale, circular DNA-histone mesostructures (DHMs). DHMs are bioengineered chromatin meshes of defined DNA and histone compositions designed as minimal mimetics of physiological extracellular chromatin structures, such as neutrophil extracellular traps (NETs).

質問

1–10/10 質問  
  1. Is the product "Human Serum, Normal (S1-100ML)" pooled from Asian populations or European populations or Africa populations or mix?

    1 回答
    1. The ethnicities of this product are not tracked. It is sourced from a mix of populations in the United States.

      役に立ちましたか?

  2. Does the certificate of analysis for this product indicate how much protein it has?

    1 回答
    1. Yes, the total protein content is lot specific and reported in the Certificate of Analysis. There is no assigned minimum or maximum specification, this information is reported on an 'as is' basis. A survey of recent lots indicates a typical range of 5.5 - 6.2 mg/dL. Please see the link below to review a lot specific Certificate:
      https://www.sigmaaldrich.com/product/mm/s1m#product-documentation

      役に立ちましたか?

  3. Is the product young donors only, old donors, or mixed ages?

    1 回答
    1. The serum is pooled from multiple donors. The batch run varies but can be between 400 to 500 donors.
      The age range is between 18 to 65 years.

      役に立ちましたか?

  4. does the serum need to be heat-inactivated?

    1 回答
    1. This serum has not been heat inactivated. If the intent is to use serum with an inactivated complement system, heat inactivation is recommended.

      役に立ちましたか?

  5. Is dialyzed human serum available?

    1 回答
    1. Dialyzed serum is not sold as a product. However, normal human serum (cat #s S1-LITER or S1-100ML) is available.
      Additionally, we provide various products that allow the client to dialyze the serum. Depending on the volume of serum to be dialyzed, any of the following products will work:
      •D-Tubes or Amicon Ultra for small volumes
      •Centricon Plus-70 for centrifuging 70 mL samples (cat # UFC701008)
      •Stirred cells along with 10 kDa MWCO ultrafiltration membrane discs for volumes up to 400 mL

      役に立ちましたか?

  6. Is the product "Human Serum, Normal (S1-100ML)" Male only, Female only or Male/Female mix?

    1 回答
    1. This product is pooled human serum, typically consisting of hundreds of male and female donors.

      役に立ちましたか?

  7. Is there any detectable thrombin in this serum?

    1 回答
    1. Unfortunately, this product is not tested for thrombin.

      役に立ちましたか?

  8. Hi, wonder if this is a pooled serum from multiple donors or a single bottle is from a single donor? thanks.

    1 回答
    1. This serum product is pooled from multiple donors. The typical batch varies but can range from 400 to 500 donors.

      役に立ちましたか?

  9. I would like to know whether it has been inactivated as I intend to use the complement components in the serum to activate the complement system in vitro. Additionally, does this serum have been previously used in complement activation studies?

    1 回答
    1. This product has not been inactivated, however it is not tested for use in compliment studies. The product may or may not be suitable for this application. See the link below for a product that may be of interest:
      https://www.sigmaaldrich.com/product/sigma/c9473.

      役に立ちましたか?

  10. Hi! I was wondering how this serum is collected and what storage agents/additives were used in the collection tubes/bags. E.g. silica in Vacutainer SST tubes

    1 回答
    1. As it states in the "Description" section, normal human serum is collected off the clot from healthy normal humans. It is a nonsterile liquid with no preservatives.

      役に立ちましたか?

レビュー

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アクティブなフィルタ

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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