"Grade I-A" originates from product listings for heparin prior to the implementation of the current catalog numbering system. This older grading system has since been phased out, but the terminology was retained in the descriptions of some current products. The M-Clarity™ Program accurately defines the current quality classification system, along with specifications listed in the product Specification Sheet and/or Certificate of Analysis.
H3393
ヘパリン ナトリウム塩 from porcine intestinal mucosa
Grade I-A, ≥180 USP units/mg
別名:
ヘパリンナトリウム
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10000 UNITS
￥4,180
25000 UNITS
￥6,160
50000 UNITS
￥7,480
100000 UNITS
￥9,955
250000 UNITS
￥20,955
500000 UNITS
￥36,135
1000000 UNITS
￥58,850
この商品について
スキップする
由来生物
Porcine intestinal mucosa
品質水準
タイプ
Grade I-A
フォーム
powder
比活性
≥180 USP units/mg
色
beige
有効pH範囲
5.0 - 7.5
溶解性
H2O: 50 mg/mL, clear, colorless to faintly yellow
アプリケーション
clinical research
diagnostic assay manufacturing
life science and biopharma
保管温度
room temp
SMILES記法
[Na+].[S](=O)(=O)(NC1C(OC(C(C1O[S](=O)(=O)O)OC4OC(C(C(C4O[S](=O)(=O)O)O)O)C(=O)O)CO)OC2C(OC(C(C2O)O[S](=O)(=O)O)OC3C(OC(C(C3O)NC(=O)C)O)CO[S](=O)(=O)O)C(=O)O)O
InChI Key
JRTRSJGZMRQDHI-UHFFFAOYSA-N
類似した製品をお探しですか？ 訪問 製品比較ガイド
1 of 4
当該品目 | H3149 | 1304038 | 1304016 |
|---|---|---|---|
| biological source Porcine intestinal mucosa | biological source Porcine intestinal mucosa | biological source - | biological source - |
| Quality Level 200 | Quality Level 200 | Quality Level - | Quality Level - |
| solubility H2O: 50 mg/mL, clear, colorless to faintly yellow | solubility H2O: 50 mg/mL | solubility - | solubility - |
| form powder | form powder | form - | form - |
| storage temp. room temp | storage temp. - | storage temp. −20°C | storage temp. −20°C |
| color beige | color beige | color - | color - |
詳細
アプリケーション
生物化学的／生理学的作用
同等製品
保管分類コード
11 - Combustible Solids
WGK
WGK 2
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, type N95 (US)
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
H3393-10KU:
H3393-1MU:
H3393-25KU:
H3393-50KU:
H3393-500KU:
H3393-100KU:
H3393-250KU:
H3393-BULK:
H3393-EW:
H3393-VAR:
Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models--association with liver and adipose tissue effects.
Xu J et al.
American Journal of Physiology. Endocrinology and Metabolism, 297, E1105-E1105 (2009)
The anti-inflammatory effects of heparin and related compounds
Young E, et al.
Thrombosis Research, 122(6) , 743-752 (2008)
L Peter Sarin et al.
Nucleic acids research, 37(4), 1182-1192 (2009-01-09)
The RNA-dependent RNA polymerase (RdRP) of double-stranded RNA (dsRNA) viruses performs both RNA replication and transcription. In order to initiate RNA polymerization, viral RdRPs must be able to interact with the incoming 3' terminus of the template and position it
Bovine immature oocytes acquire developmental competence during meiotic arrest in vitro.
Hashimoto S et al.
Biology of Reproduction, 66, 1696-1696 (2002)
Bioengineered human heparin with anticoagulant activity
Lord M S, et al.
Metabolic engineering, 38, 105-114 (2016)
資料
Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.
Uncover more about glycosaminoglycans and proteoglycans including the structure of glycosaminoglycans (GAGs), the different types of GAGs, and their functions.
Discover the role of carbohydrates in drug delivery, from solubility and stability improvement to advanced controlled-release systems.
Explore how carbohydrates function as excipients and carriers in drug delivery, with insights into mechanisms, case studies, and future trends.
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What does Grade I-A mean?
1 回答-
役に立ちましたか？
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How can I determine the shelf life / expiration / retest date of this product?
1 回答-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf役に立ちましたか？
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How do I calculate how much Heparin sodium salt I need to prevent coagulation in a gallon of cow's blood? Would it have to be dissolved in a saline solution first?
1 回答-
The typical dosage of heparin for anticoagulation can vary based on the specific application and the type of blood product. For general anticoagulation, a common range is between 5 to 30 units of heparin per milliliter of blood. For cow's blood, the amount of this product needed will depend on the desired dosage and the volume of blood, which may be found in veterinary guidelines or literature. It is advisable to dissolve it in a saline solution or sterile water before use to ensure effective administration.
役に立ちましたか？
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 回答-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
役に立ちましたか？
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please, could you explain me if this Heparin H3393 in one 'high molecolar wieght heparin'?
1 回答-
This product is a porcine heparin with a molecular weight range of 15-19 kDa. This material is considered a "high molecular weight heparin." According to the literature, low molecular weight heparins are those with a molecular weight of less than 8000 Da. See the link below to review a publication that may be helpful:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141002/役に立ちましたか？
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How many grams of sodium heparin, derived from porcine intestinal mucosa, are contained in a single vial?
1 回答-
This product is sold by units and vial content will vary from lot to lot. The minimum activity specification is 180 units/mg. The lot-specific activity is reported on the Certificate of Analysis. The following values indicate the least amounts will be present in each pack size:
10 KU: 56 mg
25 KU: 139 mg
50 KU: 278 mg
100 KU: 556 mg
250 KU: 1389 mg
500 KU: 2778 mg
1 MU: 5556 mgPlease see the link below to review a sample or lot specific Certificate:
https://www.sigmaaldrich.com/product/sial/h3393#product-documentation役に立ちましたか？
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What is the molecular weight of Heparin sodium salt?
1 回答-
The molecular weight is determined in-house for the product. The correct molecular weight range for this product is 15-19kDa.
役に立ちましたか？
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How much Heparin sodium salt, is used to prevent coagulation?
1 回答-
It is suggested to use 15 to 30 units per mL of blood.
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What is the Department of Transportation shipping information for this product?
1 回答-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
役に立ちましたか？
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What is the best way to sterilize Heparin sodium salt?
1 回答-
Although solutions may be autoclaved at 121 °C for 5 to 10 minutes, we generally recommend sterile filtration. This is because prolonged autoclaving may have an effect on its activity.
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