SAB6012074

Anti Frizzled class receptor 8 Antibody, clone 23GB5470, Rabbit Monoclonal

clone 23GB5470, recombinant rabbit monoclonal, expressed in HEK293 cells

• 別名: FZ-8, HFz8
• UNSPSCコード: 12352203

特性

• 由来生物: rabbit (Monoclonal)
• 品質水準: 100
• リコンビナント: expressed in HEK 293 cells
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: 23GB5470, recombinant monoclonal
• フォーム: buffered aqueous glycerol solution
• 分子量: 73 kDa
• 交差性: human
• 包装: vial of 1.5 mL
• 強化検証: recombinant expression; Learn more about Antibody Enhanced Validation
• sustainability: Greener Alternative Product
• 濃度: 1 mg/ml
• テクニック: flow cytometry: 1:2000; western blot: 1:1,000-1:5,000
• アイソタイプ: IgG
• Ensembl |ヒトアクセッション番号: ENSG00000177283
• NCBIアクセッション番号: NP_114072.1
• UniProtアクセッション番号: Q9H461
• 環境により配慮した代替製品カテゴリ: DfS-Developed
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... FZD8(8325)

詳細

詳細

This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]

We are committed to bringing you Greener Alternative Products. This product is a Design for Sustainability (DfS) developed product, which belongs to one of the four categories of greener alternatives. Click here to view its DfS scorecard.

免疫原

A synthesized peptide corresponding to a sequence within amino acids 640-694 of human Frizzled 8 [NP_114072.1].

物理的形状

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

その他情報

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.