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Merck

CHRM4

cholinergic receptor, muscarinic 4

Synonimy:
HM4, M4R
Gatunek:
Human CHRM4 (1132), Mouse Chrm4 (12672), Rat Chrm4 (25111), domestic guinea pig Chrm4 (100714736), naked mole-rat Chrm4 (101726411), Domestic Rabbit CHRM4 (100008791), dog CHRM4 (611314), cow CHRM4 (512928), sheep CHRM4 (101114554), domestic cat CHRM4 (101088360)
Identyfikator UniProtKB:
P08173, B2RPP4, Q0VD60, Q4VBK7
Identyfikator genu:
  • Human(1132) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. [provided by RefSeq, Jul 2008]
  • Mouse(12672) cholinergic receptor, muscarinic 4
  • Rat(25111) cholinergic receptor, muscarinic 4
  • domestic guinea pig(100714736) cholinergic receptor, muscarinic 4
  • naked mole-rat(101726411) cholinergic receptor, muscarinic 4
  • Domestic Rabbit(100008791) cholinergic receptor, muscarinic 4
  • dog(611314) cholinergic receptor, muscarinic 4
  • cow(512928) cholinergic receptor, muscarinic 4
  • sheep(101114554) cholinergic receptor, muscarinic 4
  • domestic cat(101088360) cholinergic receptor, muscarinic 4
  • chicken(423195) cholinergic receptor, muscarinic 4

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
A2251
Acetyl-β-methylcholine chloride, ≥98% (TLC), powder,
Gatunek
human
P6503
Pilocarpine hydrochloride, ≥99% (titration), powder,
Gatunek
human
O100
Oxotremorine M, solid,
Gatunek
human
P6628
Pilocarpine nitrate salt, ≥98% (HPLC),
Gatunek
human
M104
(±)-Muscarine chloride hydrate, ≥98% (HPLC),
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
B1390
Bisacodyl, analytical standard, for drug analysis,
Gatunek
human
T9778
Tropicamide, solid,
Gatunek
human
I1637
Ipratropium bromide monohydrate, ≥98% (TLC), powder,
Gatunek
human
S7882
(−)-Scopolamine N-butyl bromide, ≥98% (TLC), powder,
Gatunek
human
O2881
Oxybutynin chloride, ≥98% (TLC), powder,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
MAB1578
Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 18C7.2, clone 18C7.2, Chemicon®, from mouse,
Reaktywność gatunkowa
monkey
Zastosowanie
immunohistochemistry
immunoprecipitation (IP)
western blot
ZMS1165
Przeciwciało anty-CHRM4, klon 18C7.2 ZooMAb® mysie monoklonalne, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
affinity binding assay
immunocytochemistry
western blot
SAB4300824
Anty-CHRM4, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
MAB1576
Anti-Muscarinic Acetylcholine Receptor m4 Antibody, clone 17F10.2, purified antibody, clone 17F10.2, Chemicon®,
Reaktywność gatunkowa
monkey, mouse, rat
Zastosowanie
immunocytochemistry
immunoprecipitation (IP)
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
A8404
Amitriptyline hydrochloride, ≥98% (TLC), powder,
Gatunek
human
D4526
Doxepin hydrochloride, ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder,
Gatunek
human
51330
Harmaline, ≥95%,
Gatunek
human, rat

Small Molecule - Ligand

Numer produktu
Opis
Gatunek
A138
Aminobenztropine, solid,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
EMU046221
MISSION® esiRNA, targeting mouse Chrm4,
Gatunek
mouse