This material is extracted from a non-biological, natural source.
04238
Hydroxyapatite
puriss., meets analytical specification of Ph. Eur., BP, FCC, E341, ≥90% (calculated on glowed substance)
Synonym(s):
Calcium phosphate hydroxide, Durapatite, Hydroxylapatite
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1 KG
$127.50
About This Item
Linear Formula:
3Ca3(PO4)2 · Ca(OH)2
CAS Number:
Molecular Weight:
502.31
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
215-145-7
MDL number:
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Product Name
Hydroxyapatite, puriss., meets analytical specification of Ph. Eur., BP, FCC, E341, ≥90% (calculated on glowed substance)
InChI key
XYJRXVWERLGGKC-UHFFFAOYSA-D
InChI
1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10
SMILES string
[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O
grade
puriss.
assay
≥90% (calculated on glowed substance)
form
powder
quality
meets analytical specification of Ph. Eur., BP, FCC, E341
composition
Ca, 35-40%
impurities
residual solvents, complies
≤0.001% heavy metals (as Pb)
≤0.2% insoluble in HCl
loss
≤8% loss on ignition, 800 °C
anion traces
chloride (Cl-): ≤1500 mg/kg
fluoride (F-): ≤50 mg/kg
sulfate (SO42-): ≤5000 mg/kg
cation traces
As: ≤2 mg/kg
Cd: ≤1 mg/kg
Cu: ≤20 mg/kg
Fe: ≤400 mg/kg
Hg: ≤1 mg/kg
Pb: ≤2 mg/kg
Zn: ≤20 mg/kg
Quality Level
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1 of 4
This Item | 21223 | 900203 | 391947 |
|---|---|---|---|
| form powder | form powder | form powder | form solid |
| Quality Level 200 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| grade puriss. | grade purum p.a. | grade - | grade - |
| assay ≥90% (calculated on glowed substance) | assay ≥90% (as Ca3(PO4)2, KT) | assay - | assay - |
| quality meets analytical specification of Ph. Eur., BP, FCC, E341 | quality - | quality - | quality - |
| composition Ca, 35-40% | composition - | composition - | composition - |
Application
- New Physico-Chemical Analysis of Magnesium-Doped Hydroxyapatite in Dextran Matrix Nanocomposites.: This research article focuses on the development and characterization of magnesium-doped hydroxyapatite within a dextran matrix, emphasizing its potential applications in biomedical and tissue engineering fields (Predoi et al., 2023).
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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Mechanical properties of sintered hydroxyapatite for prosthetic applications.
Akao M ,et al.
J. Mater. Sci., 16(3), 809-812 (1981)
P Ducheyne et al.
Biomaterials, 7(2), 97-103 (1986-03-01)
Hydroxyapatite from two sources was electrophoretically deposited onto flat titanium plate material. Depending upon the deposition conditions various changes in the structure of the ceramic were identified. A well-adhering Ti-P compound was present at the interface. Hydroxyapatite oxygenated to various
Chemical characterization of silicon-substituted hydroxyapatite
Gibson I, et al.
Journal of Biomedical Materials Research, 44(4), 422-428 (1999)
Sophie E P New et al.
Circulation research, 113(1), 72-77 (2013-04-26)
We previously showed that early calcification of atherosclerotic plaques associates with macrophage accumulation. Chronic renal disease and mineral imbalance accelerate calcification and the subsequent release of matrix vesicles (MVs), precursors of microcalcification. We tested the hypothesis that macrophage-derived MVs contribute
Sergio Bertazzo et al.
Nature materials, 12(6), 576-583 (2013-04-23)
The accumulation of calcified material in cardiovascular tissue is thought to involve cytochemical, extracellular matrix and systemic signals; however, its precise composition and nanoscale architecture remain largely unexplored. Using nano-analytical electron microscopy techniques, we examined valves, aortae and coronary arteries
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Are the hydroxyapatite (product no. 0438 Lot no 92170) synthesis or obtained from naturall sources?
1 answer-
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What is the particle size of this product?
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The particle size for this product is not determined. However, other hydroxyapatite products may be of interest as the particle size is available:
900203; Hydroxyapatite, powder, 10 μm, spec. surface area ≥80 m2/g
https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/900203-BULKMKCT5305.pdf900204; Hydroxyapatite, powder, 5 μm, surface area ≥80 m2/g
https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/900204-BULKMKCT6258.pdfHelpful?
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