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Merck

33-016

PI3-激酶 HTRF ®含量测定;384 孔

The PI 3-Kinase HTRF Assay is a high-performance assay kit that provides a universal method for testing all Class I PI3-Kinases in a homogeneous format. This pack size has a screening capacity of 1 plate.

同義詞:

HTRF检测, PI 3-激酶检测

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分類程式碼代碼:
12161503
eCl@ss:
32161000
NACRES:
NA.84

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品質等級

物種活性

human, mouse

製造商/商標名

HTRF®
Upstate®

技術

activity assay: suitable (kinase)

NCBI登錄號

UniProt登錄號

檢測方法

fluorometric (HTRF)

運輸包裝

dry ice

基因資訊

human ... PIK3CA(5290)

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本產品
33-01733-03633-047
technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

species reactivity

human, mouse

species reactivity

mouse, human

species reactivity

mouse, human

species reactivity

human, mouse

manufacturer/tradename

HTRF®

manufacturer/tradename

HTRF®, Upstate®

manufacturer/tradename

HTRF®, Upstate®

manufacturer/tradename

HTRF®, Upstate®

NCBI accession no.

NM_006218.2

NCBI accession no.

NM_006218.2

NCBI accession no.

NM_006218.2

NCBI accession no.

NM_006218.2

UniProt accession no.

P42336

UniProt accession no.

P42336

UniProt accession no.

P42336

UniProt accession no.

P42336

detection method

fluorometric (HTRF)

detection method

fluorometric (HTRF)

detection method

fluorometric (HTRF)

detection method

fluorometric (HTRF)

應用

用于检测/量化:PI 3-激酶

生化/生理作用

靶标亚家族:PI3K/PI4K

包裝

试剂盒容量:384孔

其他說明

4X反应缓冲液

PIP2(底物;1mM储备液)

终止试剂A

终止试剂B

DM A检测试剂

DM B检测试剂

DM C检测试剂

法律資訊

HTRF is a registered trademark of Cis Bio International
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2


分析證明 (COA)

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Stephen Jamieson et al.
The Biochemical journal, 438(1), 53-62 (2011-06-15)
Genetic alterations in PI3K (phosphoinositide 3-kinase) signalling are common in cancer and include deletions in PTEN (phosphatase and tensin homologue deleted on chromosome 10), amplifications of PIK3CA and mutations in two distinct regions of the PIK3CA gene. This suggests drugs
James M J Dickson et al.
Bioscience reports, 33(6) (2013-08-24)
NTT (N-terminal tags) on the catalytic (p110) sub-unit of PI 3-K (phosphoinositol 3-kinase) have previously been shown to increase cell signalling and oncogenic transformation. Here we test the impact of an NT (N-terminal) His-tag on in vitro lipid and protein
Christina M Buchanan et al.
PloS one, 8(8), e71337-e71337 (2013-08-13)
In addition to lipid kinase activity, the class-I PI 3-kinases also function as protein kinases targeting regulatory autophosphorylation sites and exogenous substrates. The latter include a recently identified regulatory phosphorylation of the GM-CSF/IL-3 βc receptor contributing to survival of acute
Qin Li et al.
Toxicology research, 8(3), 353-360 (2019-06-05)
Qingkailing injection (QKLI) is a kind of multi-component traditional Chinese medicine injection. It has been widely used in clinical practice, but in recent years, it has caused more and more adverse reactions, mainly manifested as pseudo-allergic symptoms. To explore the

相關內容

This paper provides an overview of PI3-kinase and what makes them unique, their implications for cancer, their roles in signal transduction and the challenges researchers face today with advancing this reserach.

Complete PI3-Kinase Assay Solution The PI3-Kinase HTRF Assay is a high-performance assay kit that provides a universal method for assaying all Class I PI3-Kinases in a homogeneous 384 well format. Nowhere else will you find a kit that offers this level of performance. And, nowhere else you will find as many Class I PI3-Kinases available.

Signaling Product Guide: Antibodies, small molecule inhibitors, kits, assays and proteins for signaling research.

"Recognizing both the tremendous opportunities and the challenges facing cancer research, we are dedicated to developing and refining tools and technologies for the study of cancer. With our comprehensive portfolio, including the Upstate®, Chemicon®, and Calbiochem® brands of reagents and antibodies, researchers can count on dependable, high quality solutions for analyzing all the hallmarks of cancer."

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