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經驗公式（希爾表示法）:
C21H25ClN2O3 · 2HCl
CAS 編號:
分子量：:
461.81
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
跳轉至
產品名稱
西替利嗪, European Pharmacopoeia (EP) Reference Standard
InChI
1S/C21H25ClN2O3.2ClH/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26;;/h1-9,21H,10-16H2,(H,25,26);2*1H
SMILES string
OC(COCCN1CCN(C(C2=CC=C(Cl)C=C2)C3=CC=CC=C3)CC1)=O.[H]Cl.[H]Cl
InChI key
PGLIUCLTXOYQMV-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
cetirizine
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Gene Information
human ... HRH1(3269)
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本產品 | BP837 | 1102929 | BP1081 |
|---|---|---|---|
| manufacturer/tradename EDQM | manufacturer/tradename BP | manufacturer/tradename USP | manufacturer/tradename BP |
| grade pharmaceutical primary standard | grade pharmaceutical primary standard | grade pharmaceutical primary standard | grade pharmaceutical primary standard |
| application(s) pharmaceutical (small molecule) | application(s) pharmaceutical | application(s) pharmaceutical (small molecule) | application(s) pharmaceutical |
| format neat | format neat | format neat | format mixture |
| API family cetirizine | API family cetirizine | API family cetirizine | API family cetirizine |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. room temp | storage temp. 2-8°C |
Application
Cetirizine for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Biochem/physiol Actions
Cetirizine hydrochloride is a non-sedating type histamine H1-receptor antagonist.
Cetirizine hydrochloride is an orally active and selective H1-receptor antagonist. Antihistaminic; Piperazines. Non-sedating type histamine H1-receptor antagonist; major metabolite of hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
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signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral
存儲類別/等級
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Arnold Bahlmann et al.
Chemosphere, 89(11), 1278-1286 (2012-06-12)
Carbamazepine (CBZ), caffeine and cetirizine were monitored by enzyme-linked immunosorbent assays (ELISAs) in surface and wastewaters from Berlin, Germany. This fast and cost-efficient method enabled to assess the spatial and temporal variation of these anthropogenic markers in a high-throughput screening.
Macheng Yan et al.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 33(1), 60-64 (2013-04-20)
To investigate the potential rules and knowledge of Traditional Chinese Medicine (TCM) and Western Medicine (WM) treatment on chronic urticaria (CU) based on data-mining methods. Sixty patients with chronic urticaria, treated with TCM and WM, were selected. Gray correlation analyses
Ko-Haung Lue et al.
International journal of pediatric otorhinolaryngology, 76(7), 994-1001 (2012-04-20)
Supplementary consumption of probiotics may temporarily alter the intestinal microflora of infants and children, thereby preventing and treating allergic disorders. To compare the clinical efficacy of levocetirizine with that of levocetirizine plus Lactobacillus johnsonii EM1 (Lj EM1) for treating perennial
Susan D Mathias et al.
Allergy and asthma proceedings, 33(2), 186-190 (2012-04-25)
The Urticaria Patient Daily Diary, including the Urticaria Activity Score, has recently been validated in adults with chronic idiopathic urticaria (CIU), but its validity in adolescents is unknown. This study was designed to (1) assess the content validity of the
Natalie J Carter
Drugs, 72(9), 1257-1269 (2012-06-13)
Bilastine is an orally administered, second-generation antihistamine used in the symptomatic treatment of seasonal or perennial allergic rhinoconjunctivitis and urticaria. In two well designed phase III trials, 14 days' treatment with bilastine was associated with a significantly lower area under
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