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• Data Sheet: Cellicon^® Filter and Controller

  The benchtop Cellicon™ Perfusion Solution is designed to meet your perfused seed train challenges. It consists of a controller and a flat sheet cell retention filter with a single-use assembly running in tangential flow filtration mode. This easy-to-use solution increases perfusion process efficiency and provides real-time monitoring and control for reliable and consistent performance.

• Data Sheet: Cellicon^® Cell Retention Solution for Process Scale

  Embark on a journey of discovery as you delve into a wealth of technical insights and specifications, gaining a comprehensive understanding of the product's vast capabilities and unlocking its limitless potential.

• Article: Cell Retention Technology and Specialized Cell Culture Media for Intensified Upstream Processing

  This study demonstrates the use of a Cellicon^® filter and controller in an N-1 perfusion process with Cellvento^® 4CHO-X expansion medium as compared to a control seed train using shake flasks

• Article: Reproducible Scaling of a Cell Retention Filter Using the Cellicon^® Cell Retention Solution

  This page describes the design attributes of the Cellicon^® Filter Assembly and how they simplify process scale-up.

• Article: Operational and Financial Advantages of Cellicon^® Cell Retention Solution in an N-1 Perfusion Process

  The following study compares the process economics of an N-1 perfusion process at the 2,000 L scale using our Cellicon^® Cell Retention Solution versus a commercially available cell retention device

• Performance Guide: Cellicon^® Perfusion Solution

  Process Recommendations and Scalability Strategies for Optimization of Perfusion Cell Culture with the Cellicon^® Cell Retention Solution

• Application Note: Evaluation of Novel Cell Retention Technology and Cell Culture Media for N-1 Perfused Seed Train

  This study was designed to evaluate new technologies and explore the benefits of process intensification in an N-1 perfusion application. It used the Cellicon™ perfusion filter and controller, as well as the Cellvento^® 4CHO-X Expansion Medium during cell expansion. The products were evaluated based on the metrics of cell growth, viability, titer, nutrient quantities, and product quality.

• Data Sheet: Bio4C ACE™ Control Software

  This data sheet outlines the features and benefits of Bio4C ACE™ software.

• White Paper: Upstream Intensification – Enabling Perfusion Processes with Cell Retention Technologies

  In this white paper, we explore perfusion processes and how they are becoming a viable solution that can be used to address today’s processing challenges by increasing speed, reducing plant footprint, and improving productivity without compromising product quality.

• White Paper: A Cost Analysis and Evaluation of Perfused Seed Train Scenarios Through Process Modeling

  This white paper describes process modeling and comparison of process economics for a conventional upstream process and three perfused seed train alternatives in combination with either a conventional fed-batch bioreactor or high-seed fed-batch bioreactor.