MilliporeSigma

AGT

angiotensinogen (serpin peptidase inhibitor, clade A, member 8)

Synonyms:
ANHU, SERPINA8
Species:
UniProtKB ID:
Gene ID:
  • Human(183) Summary: The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Jul 2008]
  • Mouse(11606) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • Rat(24179) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • Thale Cress(815822) alanine--glyoxylate aminotransferase
  • Zebrafish(322485) angiotensinogen
  • fruit fly(40816) O-6-alkylguanine-DNA alkyltransferase
  • chicken(421543) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • dog(403783) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • domestic cat(101093714) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • cow(527114) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • sheep(101119440) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • sheep(100294599) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • naked mole-rat(101717217) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • domestic guinea pig(100724950) angiotensinogen (serpin peptidase inhibitor, clade A, member 8)

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ELISA

Product Number
Description
Species
Angiotensin II EIA Kit, for serum, plasma, culture supernatant and cell lysates,
Species
human
Human Angiotensinogen ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-AGT antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-Angiotensinogen Antibody, clone 9Q5D4, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
Anti-Angiotensin Converting Enzyme Antibody, clone 9B9, clone 9B9, Chemicon®, from mouse,
Species Reactivity
feline, hamster, human, monkey, rat
Application
ELISA
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Monoclonal Anti-AGT antibody produced in mouse, clone 3C10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot
Anti-AGT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
Angiotensin II human, ≥93% (HPLC), powder,
Species
human
Angiotensin Fragment 1-7 acetate salt hydrate, ≥90% (HPLC), powder,
Species
human
Angiotensinogen from human plasma, ≥80% (SDS-PAGE), lyophilized powder,
Species
human
Angiotensin I human acetate salt hydrate, ≥90% (HPLC), powder, suitable for mammalian cell culture,
Species
human
Angiotensinogen, Human Plasma, Native angiotensinogen from human plasma that is cleaved by renin to generate angiotensin I. It is a part of the renin-angiotensin system that regulates blood pressure and fluid balance.,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human AGT,
Species
human