11480
Azelaic acid
technical, ~85% (GC)
Synonym(s):
Nonanedioic acid
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Product Name
Azelaic acid, technical, ~85% (GC)
InChI key
BDJRBEYXGGNYIS-UHFFFAOYSA-N
InChI
1S/C9H16O4/c10-8(11)6-4-2-1-3-5-7-9(12)13/h1-7H2,(H,10,11)(H,12,13)
SMILES string
OC(=O)CCCCCCCC(O)=O
vapor density
6.5 (vs air)
vapor pressure
<1 mmHg ( 20 °C)
grade
technical
assay
~85% (GC)
bp
286 °C/100 mmHg (lit.)
mp
109-111 °C (lit.)
functional group
carboxylic acid
Quality Level
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Related Categories
1 of 4
This Item | 95054 | 8.20117 | A96150 |
|---|---|---|---|
| assay ~85% (GC) | assay ≥98.5% (GC) | assay ≥98.0% (GC) | assay 80% |
| Quality Level 200 | Quality Level 100 | Quality Level 200 | Quality Level 100 |
| mp 109-111 °C (lit.) | mp 106-112 °C, 109-111 °C (lit.) | mp 106-109 °C | mp 109-111 °C (lit.) |
| bp 286 °C/100 mmHg (lit.) | bp 286 °C/100 mmHg (lit.) | bp 237 °C/20 hPa | bp 286 °C/100 mmHg (lit.) |
| vapor density 6.5 (vs air) | vapor density 6.5 (vs air) | vapor density - | vapor density 6.5 (vs air) |
| vapor pressure <1 mmHg ( 20 °C) | vapor pressure <1 mmHg ( 20 °C) | vapor pressure 1.3 hPa ( 178.3 °C) | vapor pressure <1 mmHg ( 20 °C) |
Application
- A phase 3 randomized, double-blind, vehicle-controlled trial of azelaic acid foam 15% in the treatment of papulopustular rosacea: This study evaluates the efficacy and safety of a 15% azelaic acid foam in treating rosacea, demonstrating significant improvements in disease severity (Draelos et al., 2015).
- Comparison of the characteristics of transfersomes and protransfersomes containing azelaic acid: This research compares the properties of transfersome formulations with azelaic acid, highlighting their potential for enhanced delivery in dermatological applications (Rahmi and Pangesti, 2018).
- Enhancing the bioconversion of azelaic acid to its derivatives by response surface methodology: This article discusses optimizing the production of azelaic acid derivatives, which are crucial for cosmetic and pharmaceutical applications (Khairudin et al., 2018).
- Azelaic acid: a bio-based building block for biodegradable polymers: The study explores azelaic acid as a sustainable precursor for producing biodegradable polymers, pertinent to material science (Todea et al., 2021).
- Preparation and evaluation of azelaic acid topical microemulsion formulation: in vitro and in vivo study: This research presents a microemulsion formulation of azelaic acid, assessing its stability and skin permeability, critical for topical therapeutic applications (Hung et al., 2021).
Biochem/physiol Actions
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
410.0 °F - closed cup
flash_point_c
210 °C - closed cup
ppe
Eyeshields, Gloves, type N95 (US)
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