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MilliporeSigma

364959

N-[Tris(hydroxymethyl)methyl]acrylamide

contains ≤7% KCl, 93%

Synonym(s):

NAT, TRIS-acrylamide

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5 G

$86.80

25 G

$353.60

$86.80


Available to ship onDecember 02, 2025Details


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About This Item

Linear Formula:
H2C=CHCONHC(CH2OH)3
CAS Number:
Molecular Weight:
175.18
Beilstein/REAXYS Number:
2081162
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

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assay

93%

form

solid

contains

≤7% KCl

mp

136-141 °C (lit.)

storage temp.

2-8°C

SMILES string

OCC(CO)(CO)NC(=O)C=C

InChI

1S/C7H13NO4/c1-2-6(12)8-7(3-9,4-10)5-11/h2,9-11H,1,3-5H2,(H,8,12)

InChI key

MVBJSQCJPSRKSW-UHFFFAOYSA-N

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1 of 4

This Item
697931771465436534
assay

93%

assay

97%

assay

98%

assay

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

mp

136-141 °C (lit.)

mp

-

mp

129-146 °C

mp

-

form

solid

form

liquid

form

powder

form

viscous liquid

contains

≤7% KCl

contains

1,000 ppm monomethyl ether hydroquinone as stabilizer

contains

-

contains

200 ppm monomethyl ether hydroquinone as inhibitor

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

Application


  • Reactions of dipropilamine with unsaturated surfactants in the model oil–water system: This study investigates the reactions of dipropilamine with N-[tris(hydroxymethyl)methyl]acrylamide, highlighting potential applications in industrial and pharmaceutical processes (Simonian, 2015).

  • Water-dispersible polymer coated silica nanoparticle for turn-on fluorometric detection of Cephalexin: Utilizes N-[Tris(hydroxymethyl)methyl]acrylamide in the synthesis of a polymer to improve the detection capabilities for pharmaceutical applications, showcasing the adaptability of this monomer in enhancing sensor technologies (Sahu et al., 2022).

  • Ultrasound-triggered piezocatalytic composite hydrogels for promoting bacterial-infected wound healing: Features a hydrogel based on N-[tris(hydroxymethyl)methyl]acrylamide for medical applications, particularly in accelerating wound healing, which is crucial for drug delivery systems and tissue engineering (Liu et al., 2023).

  • An adhesive and resilient hydrogel for the sealing and treatment of gastric perforation: Describes the development of a hydrogel incorporating N-[tris(hydroxymethyl)methyl]acrylamide for potential medical use in treating internal wounds, demonstrating the material′s medical applications in a clinical setting (Webb et al., 2022).

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Anthony C Cruz et al.
Nature communications, 7, 13895-13895 (2016-12-23)
Mutations affecting the apoptosis-inducing function of the Fas/CD95 TNF-family receptor result in autoimmune and lymphoproliferative disease. However, Fas can also costimulate T-cell activation and promote tumour cell growth and metastasis. Palmitoylation at a membrane proximal cysteine residue enables Fas to
Katrina Thom et al.
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 23(12) (2018-03-29)
BackgroundPrevious studies showed low levels of circulating hepatitis E virus (HEV) in Scotland. We aimed to reassess current Scottish HEV epidemiology. Methods: Blood donor samples from five Scottish blood centres, the minipools for routine HEV screening and liver transplant recipients
Fabian Leinisch et al.
Free radical biology & medicine, 112, 240-252 (2017-08-02)
Protein oxidation is a frequent event as a result of the high abundance of proteins in biological samples and the multiple processes that generate oxidants. The reactions that occur are complex and poorly understood, but can generate major structural and
M Kozulić et al.
Analytical biochemistry, 163(2), 506-512 (1987-06-01)
We describe in detail the synthesis of an acrylic monomer, N-acryloyl-tris(hydroxy-methyl)aminomethane (NAT), which was successfully used for the preparation of gels for electrophoresis and isoelectric focusing. The polymerization kinetics and transparency of the poly(NAT) gels crosslinked by N,N'-methylenebisacrylamide (Bis) are
Ashish C Shrestha et al.
Transfusion, 56(12), 3086-3093 (2016-10-21)
Hepatitis E virus (HEV) poses a risk to transfusion safety. In Australia, locally acquired HEV is rare and cases are mainly reported in travelers returning from countries endemic for HEV. The risk posed by HEV to transfusion safety in Australia

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