All Photos(2)

C8552

Sigma-Aldrich

Cytidine 5′-triphosphate disodium solution

HPLC purified, aqueous solution for RNA polymerase transcription

Synonym(s):
CTP-Na2
Empirical Formula (Hill Notation):
C9H16N3O14P3Na2
CAS Number:
Molecular Weight:
529.14
MDL number:
PubChem Substance ID:
NACRES:
NA.52

Quality Level

form

liquid

concentration

95-105 mM in H2O (adjusted to pH 7 with Sodium Hydroxide)

color

colorless

foreign activity

DNase and RNase, none detected

shipped in

dry ice

storage temp.

−20°C

SMILES string

[Na+].[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O

InChI

1S/C9H16N3O14P3.2Na/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18);;/q;2*+1/p-2/t4-,6-,7-,8-;;/m1../s1

InChI key

NFQMDTRPCFJJND-WFIJOQBCSA-L

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Related Categories

Application

Cytidine 5′-triphosphate disodium salt is used as a nucleoside triphosphate for RNA synthesis reactions.
For use in DNA-dependent RNA polymerase transcription

Biochem/physiol Actions

CTP is incorporated into RNA via phosphodiester bond formation catalyzed by various RNA polymerases.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Certificate of Origin

Sambrook, J., et al.
Molecular Cloning: A Laboratory Manual, 5-5 (1989)
Xi Liu et al.
Anti-cancer drugs, 25(6), 690-703 (2014-03-29)
Treatment of mammalian cells with chemotherapeutic drugs can result in perturbations of nucleotide pools. Monitoring these perturbations in cultured tumor cells from human sources is useful for assessment of the effect of drug therapy and a better understanding of the

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