P1411

Sigma-Aldrich

Polymyxin B-Agarose

aqueous glycerol suspension

MDL number:
NACRES:
NA.56

Quality Level

form

aqueous glycerol suspension

extent of labeling

~1 mg per mL

matrix

Cross-linked 4% beaded agarose

matrix activation

cyanogen bromide

matrix attachment

amino

matrix spacer

1 atom

capacity

200-500 μg/mL binding capacity (lipopolysaccharide)(from Escherichia coli serotype 0128:B12)

storage temp.

2-8°C

Application

Polymyxin B-agarose is used in protein chromatography, affinity chromatography and specialty resins. Polymyxin B-agarose has been used to study periodontitis and endodontic infections as well as obesity and type 2 diabetes.
Useful for removal of endotoxins from solutions

Packaging

5, 10 mL in glass bottle

Physical form

Suspension in 50% glycerol containing 0.02% sodium azide

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Martín López et al.
Journal of immunology (Baltimore, Md. : 1950), 170(5), 2409-2416 (2003-02-21)
Macrophages infected with Mycobacterium tuberculosis undergo increased rates of apoptosis. Important objectives are to define the microbial factors that cause apoptosis, the mechanisms involved and the impact on infection. The 19-kDa M. tuberculosis glycolipoprotein (p19) is both cell wall-associated and...
J Gil et al.
Cancer research, 50(22), 7301-7306 (1990-11-15)
We have shown previously that IgM from Ehrlich tumor (ET)-immunized mice, recognizing ET cell surface carbohydrates, protects control mice to a subsequent tumor challenge. The factors involved in such IgM-mediated protection were unknown, since it was independent of complement activation....
A C Issekutz
Journal of immunological methods, 61(3), 275-281 (1983-07-29)
Endotoxins liberated by gram-negative bacteria are frequent contaminants of aqueous and physiological solutions. Because of their potent biological effects in vivo and in vitro, it is often necessary to eliminate even minute quantities of endotoxin from such solutions. A process...
Dina B AbuSamra et al.
Cells, 10(2) (2021-02-13)
Chemokines are an extended group of chemoattractant cytokines responsible for the recruitment of leukocytes into tissues. Among them, interferon-γ-inducible protein 10 (CXCL10) is abundantly expressed following inflammatory stimuli and participates in the trafficking of monocytes and activated T cells into...
P J Jagielo et al.
The American journal of physiology, 270(6 Pt 1), L1052-L1059 (1996-06-01)
To investigate the role of endotoxin in grain dust-induced airway inflammation, we reduced the endotoxin activity from extracts of corn dust (CDE), using three distinct methods, and determined the effect of endotoxin activity on the in vitro and in vivo...

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