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Well-defined ruthenium(II) carboxylate as catalyst for direct C-H/C-O bond arylations with phenols in water.

Organic letters (2012-04-13)
Lutz Ackermann, Jola Pospech, Harish Kumar Potukuchi
ABSTRACT

The ruthenium(II) carboxylate complex [Ru(O(2)CMes)(2)(p-cymene)] enabled efficient direct arylations of unactivated C-H bonds with easily available, inexpensive phenols. Extraordinary chemoselectivity of the well-defined ruthenium catalyst set the stage for challenging C-H/C-O bond functionalizations to occur under solvent-free conditions as well as in water, and allowed first direct C-H bond arylations with user-friendly diaryl sulfates as electrophiles.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
p-Cymene, 99%
Sigma-Aldrich
p-Cymene, ≥97%, FG
Supelco
p-Cymene, analytical standard
Supelco
p-Cymene, certified reference material, TraceCERT®