This product is provided to researchers, and it is labeled "For R&D Use Only. Not for drug, household or other use." 4MUPro is a dietary supplement from Profound Products. Product M1381 cannot be used as a dietary supplement, or for any human or veterinary application.
M1381
4-Methylumbelliferone
≥98%
Synonym(s):
β-Methylumbelliferone, 4-MU, 7-Hydroxy-4-methylcoumarin
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| Size/SKU | Availability | Price |
|---|---|---|
25 g | Check Cart for Availability | $42.60 |
100 g | Check Cart for Availability | $80.90 |
About This Item
Empirical Formula (Hill Notation):
C10H8O3
CAS Number:
Molecular Weight:
176.17
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
201-986-7
Beilstein/REAXYS Number:
142217
MDL number:
Assay:
≥98%
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Quality Segment
assay
≥98%
color
off-white to yellow
fluorescence
λex 372 nm; λem 445 nm in ethanol
SMILES string
CC1=CC(=O)Oc2cc(O)ccc12
InChI
1S/C10H8O3/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5,11H,1H3
InChI key
HSHNITRMYYLLCV-UHFFFAOYSA-N
Application
4-Methylumbelliferone is primarily used in synthesizing medicinal compounds and as a building block for fluorescent probes. Applications include synthesis of:
- coumarin triazole derivatives as potential antimicrobial agents.
- coumarin salen-based fluorescence sensors for Mg2+ detection.
- pyranocoumarin derivatives as anti-hyperglycemic and anti-dyslipidemic agents.
- coumarin piperazine derivatives as potential multireceptor atypical antipsychotics.
- 4-methylumbelliferyl T-antigen as a substrate for endo-α-N-acetylgalactosaminidase.
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This Item | |||
|---|---|---|---|
| description ≥98% | description European Pharmacopoeia (EP) Reference Standard | description ≥98% (HPLC), crystalline | description sulfatase substrate |
| assay ≥98% | assay - | assay ≥98% (HPLC) | assay ≥99% (HPLC) |
| Quality Level 200 | Quality Level - | Quality Level 200 | Quality Level 200 |
| color off-white to yellow | color - | color yellow | color - |
| fluorescence λex 372 nm; λem 445 nm in ethanol | fluorescence - | fluorescence - | fluorescence λex 334 nm; λem 370 nm (pH 10.4), λex 360 nm; λem 449 nm (Reaction products) |
Storage Class
11 - Combustible Solids
PPE (personal protective equipment)
dust mask type N95 (US), Eyeshields, Gloves
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For 4-Methylumbelliferone, does this come as bulk powder? Can I use it to replace 4MUPro from Profound products? Thank you.
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How can I determine the shelf life / expiration / retest date of this product?
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdfHelpful?
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Does this exist as lyo or liquid product? if lyo, is there a recommended solvent or formulation to reconstitute the product?
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This product is supplied as a powder. The material is tested for solubility in methanol at 50 mg/mL and is also reported to be soluble in glacial acetic acid, slightly soluble in ether or chloroform. Please see the link below to review additional information available in the product datasheet:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/288/023/m1381pis.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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