223859

(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide

98%

• Empirical Formula (Hill Notation): C₂₂H₂₄BrO₂P
• CAS Number: 52509-14-5
• Molecular Weight: 431.30
• NACRES: NA.22
• PubChem Substance ID: 24853408
• UNSPSC Code: 12352107
• EC Number: 257-977-3
• MDL number: MFCD00011966

Properties

• Product Name: (1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide, 98%
• InChI key: FRHRVQQUICVJDG-UHFFFAOYSA-M
• InChI: 1S/C22H22O2P.BrH/c1-4-10-19(11-5-1)25(18-22-23-16-17-24-22,20-12-6-2-7-13-20)21-14-8-3-9-15-21;/h1-15,22H,16-18H2;1H/q+1;/p-1
• SMILES string: [Br-].C1COC(C[P+](c2ccccc2)(c3ccccc3)c4ccccc4)O1
• assay: 98%
• reaction suitability: reaction type: C-C Bond Formation
• mp: 193-195 °C (lit.)
• functional group: ether; phosphine

Description

Application

Reactant for:

• Preparation of a ratiometric fluorescent probe for specific detection of cysteine over homocysteine and glutathione
• Microwave-assisted synthesis of KN-93 as inhibitor of calmodulin kinase II
• Preparation of fluorinated spirobenzofuran piperidines as s1 receptor ligands
• Synthesis and antitumor agents
• Regio-selective preparation of indole derivatives via rhodium-catalyzed domino hydroformylation/indolization

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302 + H312 + H332,H315,H319,H335
• pcodes: P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves