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763896

DL-α-Tocopherol methoxypolyethylene glycol succinate

powder

Sustainability features

Synonym(s):

Polyethylene glycol, TPGS-750-M

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Size/SKUAvailabilityPrice
1 g
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$59.90
10 g
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$398.00
25 g
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$784.00
100 g
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$1,550.00

About This Item

CAS Number:
MDL number:
NACRES:
NA.22
UNSPSC Code:
51171641

$59.90


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Product Name

DL-α-Tocopherol methoxypolyethylene glycol succinate,

form

powder

Quality Segment

reaction suitability

reaction type: phase-transfer, reagent type: catalyst
reaction type: C-H Activation, reagent type: surfactant

sustainability

Sustainability features

transition temp

Tm 29-34

greener alternative category

General description

Learn More at the Professor and Product Portal of Professor Bruce Lipshutz.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product TPGS-750-M is a lead surfactant for many transition metal-catalyzed cross-couplings and has been enhanced for catalytic efficiency. Find details here.

Application

DL-α-Tocopherol methoxypolyethylene glycol succinate (TPGS-750-M), a biodegradable and water-soluble derivative of natural vitamin E, is used as an environmentally benign nonionic surfactant in metal-catalyzed cross-coupling reactions in water. It is used in Heck, Suzuki-Miyaura, Sonogashira, and Negishi like couplings reactions. It can also be utilized in aminations, C-H activations, and olefin metathesis reactions.
TPGS-750-M can also be employed in:
  • The nucleophilic aromatic substitution reaction of aryl and heteroaryl halides with nitrogen, oxygen, and sulfur nucleophiles under mild conditions.
  • The preparation of quinoxaline-2,3 diones from quinoxalinones via C(sp2)-H hydroxylation reaction.
  • The intramolecular N-arylation of amines using a copper catalyst.

Other Notes

Watch Professor Lipshutz talk about TPGS-750-M in this webinar:
From milligrams to kilograms: synthetic chemistry following nature′s lead

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This Item
73385776391857668
description

-

description

2 wt. % in H2O

description

5 wt. % in H2O

description

BioXtra, water soluble vitamin E conjugate

form

powder

form

liquid

form

liquid

form

powder, crystals or chunks

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

200

reaction suitability

reagent type: catalyst
reaction type: C-H Activation, reagent type: surfactant, reaction type: phase-transfer

reaction suitability

reaction type: phase-transfer, reagent type: surfactant, reagent type: catalyst
reaction type: Bucherer Carbazole Synthesis

reaction suitability

reaction type: phase-transfer, reagent type: catalyst
reaction type: C-H Activation, reagent type: surfactant

reaction suitability

-

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

greener alternative product characteristics

Catalysis
Learn more about the Principles of Green Chemistry.

greener alternative product characteristics

-

greener alternative category

, Aligned

greener alternative category

Aligned,

greener alternative category

Aligned,

greener alternative category

-

transition temp

Tm 29-34

transition temp

-

transition temp

-

transition temp

-


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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