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763918

DL-α-Tocopherol methoxypolyethylene glycol succinate solution

5 wt. % in H2O, liquid

Sustainability features

Synonym(s):

Polyethylene glycol, TPGS-750-M

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Size/SKUAvailabilityPrice
10 mL
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$61.30
50 mL

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$229.00
100 mL
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$425.00
500 mL
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$1,680.00

About This Item

Linear Formula:
(C2H4O)nC34H56O5
CAS Number:
MDL number:
NACRES:
NA.22
UNSPSC Code:
51171641
eCl@ss:
32150312

$61.30


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Product Name

DL-α-Tocopherol methoxypolyethylene glycol succinate solution, 5 wt. % in H2O

form

liquid

Quality Segment

reaction suitability

reaction type: phase-transfer, reagent type: catalyst
reaction type: C-H Activation, reagent type: surfactant

IVD

for in vitro diagnostic use

sustainability

Sustainability features

concentration

5 wt. % in H2O

refractive index

n20/D 1.340

density

0.981 g/mL at 25 °C

greener alternative category

General description

This product aligns with one or more of the 12 Principles of Green ChemistryThis product TPGS-750-M is a lead surfactant for many transition metal-catalyzed cross-couplings and has been enhanced for catalytic efficiency. Find details here.
Learn More at the Professor and Product Portal of Professor Bruce Lipshutz.

Application

Nonionic amphile used to increase aqueous solubility of lipophilic catalysts and substrates. Olefin metathesis, Sonogashira, Suzuki-Miyaura, and Buchwald cross-coupling reactions have been successfully performed in aqueous media employing TPGS-750-M.
Second generation amphiphile which forms micelles upon dissolution in water allowing a variety of cross-coupling reactions to take place in water instead of organic solvent.

Included among the possible reactions are:
  • Olefin metathesis
  • Pd-catalyzed cross coupling reactions including Heck, Suzuki-Miyaura, Sonogashira and Buchwald-Hartwig reactions
  • C-H activation reactions

Second generation amphiphile for cross-coupling reactions in water

Other Notes

Watch Professor Lipshutz talk about TPGS-750-M in this webinar:
From milligrams to kilograms: synthetic chemistry following nature′s lead

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form

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Quality Level

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Quality Level

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Quality Level

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Quality Level

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reaction suitability

reagent type: surfactant, reaction type: phase-transfer, reagent type: catalyst
reaction type: C-H Activation

reaction suitability

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reaction suitability

reagent type: surfactant, reagent type: catalyst
reaction type: C-H Activation, reaction type: phase-transfer

reaction suitability

-

density

0.981 g/mL at 25 °C

density

1.002 g/mL at 25 °C

density

-

density

-

concentration

5 wt. % in H2O

concentration

2 wt. % in H2O

concentration

-

concentration

≥25% (ALPHA TOCOPHEROL)

IVD

for in vitro diagnostic use

IVD

-

IVD

-

IVD

-


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Storage Class

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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