Skip to Content
MilliporeSigma

Key Documents

View All Documentation

Skip To

155195

N,O-Bis(trimethylsilyl)trifluoroacetamide

≥99%

Synonym(s):

BSTFA

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Pack SizeSKUAvailabilityPrice
5 g

Available to ship TODAYfromMILWAUKEE

$40.80
25 g

Available to ship TODAYfromMILWAUKEE

$113.00
100 g

Available to ship TODAYfromMILWAUKEE

$396.00

About This Item

Linear Formula:
CF3C[=NSi(CH3)3]OSi(CH3)3
CAS Number:
25561-30-2
Molecular Weight:
257.40
UNSPSC Code:
12352111
NACRES:
NA.22
PubChem Substance ID:
24849493
EC Number:
247-103-9
Beilstein/REAXYS Number:
2050024
MDL number:
MFCD00008269
Assay:
≥99%
Form:
liquid

$40.80

Available to ship TODAYDetails

​
Request a Bulk Order
​
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

grade

synthesis grade

assay

≥99%

form

liquid

refractive index

n20/D 1.384 (lit.)

bp

45-50 °C/14 mmHg (lit.)

density

0.969 g/mL at 25 °C (lit.)

functional group

fluoro

SMILES string

C[Si](C)(C)O\C(=N\[Si](C)(C)C)C(F)(F)F

InChI

1S/C8H18F3NOSi2/c1-14(2,3)12-7(8(9,10)11)13-15(4,5)6/h1-6H3/b12-7+

InChI key

XCOBLONWWXQEBS-KPKJPENVSA-N

General description

N,O-Bis(trimethylsilyl)trifluoroacetamide is an organosilicon reagent for trimethylsilylation, deprotection, dehydrogenation, allylic alkylation, nitronate formation, and Claisen rearrangement.

BSTFA is a silylating agent used in the synthesis of 4-Quinolones.

Application

N,O-Bis(trimethylsilyl)trifluoroacetamide can be used as a derivatization reagent for the determination of the estrogens estrone and 17α-ethinylestradiol by gas chromatography-mass spectrometry.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
1522215209B-023
N,O-Bis(trimethylsilyl)trifluoroacetamide ≥99%

Sigma-Aldrich

155195

N,O-Bis(trimethylsilyl)trifluoroacetamide

N,O-Bis(trimethylsilyl)trifluoroacetamide derivatization grade (GC derivatization), LiChropur™, ≥99.0%

Supelco

15222

N,O-Bis(trimethylsilyl)trifluoroacetamide

N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane derivatization grade (GC derivatization), LiChropur™, contains 10% TMCS, 98% (excluding TMCS)

Supelco

15209

N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane

BSTFA (with 1% TMCS) kit of 10 × 1 mL, analytical standard, Cerilliant®

Supelco

B-023

BSTFA (with 1% TMCS)

assay

≥99%

assay

≥99.0% (GC)

assay

≥97.5% (excluding TMCS, GC), 98% (excluding TMCS)

assay

-

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

100

refractive index

n20/D 1.384 (lit.)

refractive index

n20/D 1.384 (lit.)

refractive index

n20/D 1.384 (lit.)

refractive index

n20/D 1.384 (lit.)

density

0.969 g/mL at 25 °C (lit.)

density

0.969 g/mL at 25 °C (lit.)

density

0.97 g/mL (lit.)

density

0.969 g/mL at 25 °C (lit.)

bp

45-50 °C/14 mmHg (lit.)

bp

45-50 °C/14 mmHg (lit.)

bp

45-50 °C/14 mmHg (lit.)

bp

45-50 °C/14 mmHg (lit.)

form

liquid

form

liquid

form

liquid

form

-

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

93.2 °F

flash_point_c

34 °C

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCN8237
BCCN5862
BCCL9196
BCCL4285
BCCK2077

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Synthesis of 4-Quinolones: N, O-Bis (trimethylsilyl) acetamide-Mediated Cyclization with Cleavage of Aromatic C--O Bond
Pisa O, et al.
European Journal of Organic Chemistry, 2016, 2336-2350 (2016)
E Teixidó et al.
Journal of chromatography. A, 1135(1), 85-90 (2006-10-03)
A new, simple and selective method for the analysis of 5-hydroxymethylfurfural (HMF) in foods by gas chromatography coupled to mass spectrometry (GC-MS) is proposed. Several derivatising procedures based on the formation of an HMF silylated derivative using different reagents were
Hidenori Matsukami et al.
The Science of the total environment, 493, 672-681 (2014-07-06)
Chlorinated and non-halogenated organophosphorus flame retardants (OPFRs) including tris(2-chloroisopropyl) phosphate (TCIPP), diethylene glycol bis(di(2-chloroisopropyl) phosphate) (DEG-BDCIPP), triphenyl phosphate (TPHP), and bisphenol A bis(diphenyl phosphate) (BPA-BDPP) have been used increasingly as alternatives to polybrominated diphenyl ethers and other brominated flame retardants.
View All Related Papers

Global Trade Item Number

SKUGTIN
155195-500G04061833498675
155195-100G04061837789441
155195-25G04061838741950
155195-5G04061837789458

Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    0 answers

Reviews

No rating value

Active Filters