910481
Pomalidomide-PEG6-butyl CO2H
≥95%
Promotion Available
Synonym(s):
1-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-1-oxo-3,6,9,12,15,18-hexaoxapentacosan-25-oic acid, Crosslinker–E3 Ligase ligand conjugate, Pomalidomide conjugate, Pomalidomide-2-2-2-2-2-2-6-acid, Protein degrader building block for PROTAC® research, Template for synthesis of targeted protein degrader
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| Size/SKU | Availability | Price |
|---|---|---|
50 mg | Check Cart for Availability | $1,300.00 |
About This Item
ligand
pomalidomide
Quality Segment
assay
≥95%
form
chunks
reaction suitability
reactivity: amine reactive, reagent type: ligand-linker conjugate
technique(s)
targeted protein degradation: suitable
functional group
carboxylic acid
storage temp.
2-8°C
SMILES string
O=C(C(CC1)N(C2=O)C(C3=C2C=CC=C3NC(COCCOCCOCCOCCOCCOCCCCCCC(O)=O)=O)=O)NC1=O
InChI
1S/C32H45N3O13/c36-26-10-9-25(30(40)34-26)35-31(41)23-6-5-7-24(29(23)32(35)42)33-27(37)22-48-21-20-47-19-18-46-17-16-45-15-14-44-13-12-43-11-4-2-1-3-8-28(38)39/h5-7,25H,1-4,8-22H2,(H,33,37)(H,38,39)(H,34,36,40)
InChI key
APHLTAOXSKRLNL-UHFFFAOYSA-N
Application
Other Notes
Portal: Building PROTAC® Degraders for Targeted Protein Degradation
Targeted Protein Degradation by Small Molecules
Small-Molecule PROTACS: New Approaches to Protein Degradation
Targeted Protein Degradation: from Chemical Biology to Drug Discovery
Impact of linker length on the activity of PROTACs
Legal Information
1 of 1
This Item | |||
|---|---|---|---|
| description ≥95% | description - | description 95% | description - |
| form chunks | form solid | form powder or crystals | form liquid |
| functional group carboxylic acid | functional group carboxylic acid | functional group carboxylic acid | functional group carboxylic acid |
| ligand pomalidomide | ligand pomalidomide | ligand pomalidomide | ligand pomalidomide |
| assay ≥95% | assay - | assay 95% | assay ≥95% |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 200 |
Storage Class
13 - Non Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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