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8.03235

N,N-Dimethylacetamide

for synthesis

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Synonym(s):

N,N-Dimethylacetamide, Acetic acid dimethylamide, Acetyldimethylamine, DMA

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1 L
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$66.50
2.5 L
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$143.00
25 L
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$617.00

About This Item

Linear Formula:
CH3CON(CH3)2
CAS Number:
Molecular Weight:
87.12
UNSPSC Code:
12352111
EC Index Number:
204-826-4
NACRES:
NA.22
MDL number:
Assay:
≥99% (GC)
Grade:
synthesis grade
Bp:
165-166 °C/1013 hPa
Vapor pressure:
1.76 hPa ( 20 °C)

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grade

synthesis grade

Quality Segment

vapor pressure

1.76 hPa ( 20 °C)

assay

≥99% (GC)

form

liquid

autoignition temp.

400 °C

potency

5830 mg/kg LD50, oral (Rat)

expl. lim.

1.7-11.5 % (v/v)

dilution

(for synthesis)

pH

4 (20 °C, 200 g/L in H2O)

bp

165-166 °C/1013 hPa

mp

-20 °C

transition temp

flash point 64 °C

solubility

soluble >1000 g/L

density

0.94 g/cm3 at 20 °C

storage temp.

2-30°C

SMILES string

N(C)(C)C(=O)C

InChI

1S/C4H9NO/c1-4(6)5(2)3/h1-3H3

InChI key

FXHOOIRPVKKKFG-UHFFFAOYSA-N

General description

N,N-Dimethylacetamide (DMAc) is a water-miscible organic solvent used in the synthesis of styrene, vinyl resin, linear polyester, acrylic fiber, plastic, pesticide, and synthetic leather. It participates in dehydrogenation, dehydration, halogenation, deprotonation reactions and reductive carbonylation of transition metals. It can also act as catalysts, promoters, halogen/alkoxy or hydroxyl/halogen exchange mediators, reducing agents, and sources of the base.

Application

N,N-Dimethylacetamide is used as a solvent:
  • In the synthesis of poly(amide-hydrazide)s–graphene composites.
  • In the synthesis of N,N′-1,2-ethanediylbis-(4-hydroxy-pentanamide) and 4-hydroxy-N-(2- hydroxyethyl)-pentanamide based polyurethanes in presence of triethylamine catalyst.

Features and Benefits

N,N-Dimethylacetamide has :
  • High dissolution power of various substrate. 
  • High capacity to solvate anions.

Analysis Note

Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.940 - 0.942
Water (K. F.): ≤ 0.30 %
Identity (IR): passes test


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pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Repr. 1B

wgk

WGK 2

flash_point_f

147.2 °F - closed cup

flash_point_c

64 °C - closed cup

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects



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Questions

1–3 of 3 Questions  
  1. While the previous CoA from 2025 specifies the color/visibility as "colorless", this new batch specifies it as "<5, Hazen". How can I be sure that it's colorless? This'll be used for manufacturing and any type of even slight coloration will be a risk.

    1 answer
    1. The product is considered colorless, as values below 5 Hazen (and even up to 10 Hazen) are not visibly distinguishable from clear.

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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