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77626

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide

derivatization grade (GC derivatization), LiChropur™, ≥98.0% (GC)

Synonym(s):

MTBSTFA

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Size/SKUAvailabilityPrice
10 mL
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$300.00
10 x 1 mL
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$391.00

About This Item

Linear Formula:
CF3CON(CH3)Si(CH3)2C(CH3)3
CAS Number:
Molecular Weight:
241.33
NACRES:
NA.22
UNSPSC Code:
12352111
Beilstein/REAXYS Number:
3606546
MDL number:
eCl@ss:
32150917

$300.00


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grade

derivatization grade (GC derivatization)

Quality Segment

assay

≥98.0% (GC)

form

liquid

quality

LiChropur™

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

technique(s)

HPLC: suitable, LC/MS: suitable, gas chromatography (GC): suitable, ion chromatography: suitable

refractive index

n20/D 1.402 (lit.)

bp

172-175 °C (lit.)

density

1.036 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CN(C(=O)C(F)(F)F)[Si](C)(C)C(C)(C)C

InChI

1S/C9H18F3NOSi/c1-8(2,3)15(5,6)13(4)7(14)9(10,11)12/h1-6H3

InChI key

QRKUHYFDBWGLHJ-UHFFFAOYSA-N

General description

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide is a silylating reagent which replaces the active hydrogen with tert-Butyldimethylsilyl group. The tert-Butyldimethylsilyl derivatives are found to be more resistant to hydrolysis and stable compared to trimethylsilyl (TMS) derivatives. This reagent is suitable for GC-MS analysis since it produces mass spectra, which can be easily interpreted. It is widely used for the silylation of different alcohols, thiols, phenols, carboxylic acids, amines, and amides.

Application

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide may be used as a derivatizing reagent for the determination of methionine sulfoxide and methionine in blood plasma and chlorpyrifos, diazinon and their major metabolites in sludge and sludge-fertilized agricultural soils using gas-chromatography coupled to mass spectrometry technique.

Other Notes

Discover LiChropur™ reagents ideal for HPLC or LC-MS analysis

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

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derivatization grade (GC derivatization), LiChropur™, ≥98.0% (GC)

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quality

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grade

derivatization grade (GC derivatization)

grade

derivatization grade

grade

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grade

derivatization grade ((GC derivatization))

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100

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100

form

liquid

form

liquid

form

liquid

form

liquid

technique(s)

gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

gas chromatography (GC): suitable

assay

≥98.0% (GC)

assay

>97%

assay

≥95%

assay

≥95.0% (GC)


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Flash Point (°F)

113.0 °F - closed cup

Flash Point (°C)

45 °C - closed cup



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