Skip to Content
MilliporeSigma

375934

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide

≥95%, with 1% tert-Butyldimethylchlorosilane

Synonym(s):

MTBSTFA+TBDMSCl, 99:1, N-Methyl-N-tert-butyldimethylsilyltrifluoroacetamide, MTBSTFA + 1% TBDMSCl, Silylating mixture VI

Slide 1 of 1
Sign In to View Organizational & Contract Pricing.

Select a Size

5 ML

$192.00

10 X 1 ML

$254.00

25 ML

$424.00

$192.00

Available to ship TODAYDetails

Request a Bulk Order

About This Item

Empirical Formula (Hill Notation):
C9H18F3NOSi
CAS Number:
77377-52-7
Molecular Weight:
241.33
UNSPSC Code:
12352001
PubChem Substance ID:
24863412
NACRES:
NA.22
Beilstein/REAXYS Number:
3606546
MDL number:
MFCD00009671

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide with 1% tert-Butyldimethylchlorosilane, ≥95%

SMILES string

CN(C(=O)C(F)(F)F)[Si](C)(C)C(C)(C)C

InChI

1S/C9H18F3NOSi/c1-8(2,3)15(5,6)13(4)7(14)9(10,11)12/h1-6H3

InChI key

QRKUHYFDBWGLHJ-UHFFFAOYSA-N

assay

≥95%

form

liquid

contains

1% TBDMSCl

functional group

amine
fluoro

storage temp.

−20°C

Quality Level

100

Looking for similar products? Visit Product Comparison Guide

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
0094239488215238
N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide with 1% tert-Butyldimethylchlorosilane ≥95%

Sigma-Aldrich

375934

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide with 1% tert-Butyldimethylchlorosilane

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide with 1% tert-Butyldimethylchlorosilane LiChropur™, ≥95.0% (GC)

Supelco

00942

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide with 1% tert-Butyldimethylchlorosilane

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide >97%

Sigma-Aldrich

394882

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide

N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane derivatization grade (GC derivatization), LiChropur™, contains 1% TMCS, 99% (excluding TMCS)

Supelco

15238

N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane

assay

≥95%

assay

≥95.0% (GC)

assay

>97%

assay

≥98.5% (excluding chlorotrimethylsilane, GC), 99% (excluding TMCS)

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

100

form

liquid

form

liquid

form

liquid

form

liquid

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

contains

1% TBDMSCl

contains

-

contains

-

contains

-

functional group

amine

functional group

-

functional group

amine, fluoro

functional group

-

Application

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide with 1% tert-butyldimethylchlorosilane is commonly used for the preparation of N-tert-butyldimethylsilyl ethanolamines resulting from the hydrolysis of nitrogen mustards. It is also used for selective O-silylation of N,O-diacylhydroxyl amines.

comparable product

Product No.
Description
Pricing

related product

Product No.
Description
Pricing

19905

tert-Butyl(chloro)dimethylsilane, ≥95.0% (GC)

190500

tert-Butyldimethylsilyl chloride, reagent grade, 97%

473464

tert-Butylchlorodimethylsilane solution, 50 wt. % in toluene

384429

tert-Butyldimethylsilyl chloride solution, 1.0 M in methylene chloride

372951

tert-Butyldimethylsilyl chloride solution, 1.0 M in THF

226149

tert-Butyldimethylsilyl trifluoromethanesulfonate, reagent grade, 98%

250236

1-(tert-Butyldimethylsilyl)imidazole, ≥95%

33092-U

tert-Butyldimethylsilylimidazole solution, TBDMSIM in DMF, pkg of 10 × 1 mL

06735

tert-Butyldimethylsilyl chloride, LiChropur™, ≥99.0% (GC)

56563

tert-Butyldimethylsilyl trifluoromethanesulfonate, derivatization grade (GC derivatization), LiChropur™, ≥98.0% (T)

00942

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide with 1% tert-Butyldimethylchlorosilane, LiChropur™, ≥95.0% (GC)

44795

N,O-Bis(tert-butyldimethylsilyl)acetamide, derivatization grade (GC derivatization), LiChropur™, ≥98.0% (GC)

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

113.0 °F - closed cup

flash_point_c

45 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCN1340
BCCJ2964
BCCG3071
BCCB0590
BCBX5506

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Organometallics, 23, 2157-2161 (2004)
Tsubasa Nakajima et al.
Plant & cell physiology, 55(9), 1605-1612 (2014-06-28)
Cyanobacteria have flexible metabolic capability that enables them to adapt to various environments. To investigate their underlying metabolic regulation mechanisms, we performed an integrated analysis of metabolic flux using transcriptomic and metabolomic data of a cyanobacterium Synechocystis sp. PCC 6803
Xiaowei Wang et al.
Journal of chromatography. A, 1216(35), 6267-6273 (2009-07-31)
A sample pretreatment method for the determination of 18 chlorophenols (CPs) in aqueous samples by derivatization liquid-phase microextraction (LPME) was investigated using gas chromatography-mass spectrometry. Derivatization reagent was spiked into the extraction solvent to combine derivatization and extraction into one
R Montes et al.
Journal of chromatography. A, 1216(2), 205-210 (2008-12-17)
A fast and novel sample preparation procedure for the determination of triclosan (TCS) and methyltriclosan (MTCS) in water samples is presented. Dispersive liquid-liquid microextraction, using a ternary mixture consisting of a disperser, an extractant and N-methyl-N-(tert-butyldimethylsilyl)trifluoroacetamide (MTBSTFA) as derivatization reagent
Isaac Ohsawa et al.
Journal of chromatography. A, 1122(1-2), 242-248 (2006-05-19)
A method for determining N-ethyldiethanolamine (EDEA), N-methyldiethanolamine (MDEA) and triethanolamine (TEA), hydrolysis products of nitrogen mustards, in water, urine and blood samples using gas chromatography-mass spectrometry (GC-MS) after derivatization by tert-butyldimethylsilylation (TBDMS) is described. The sample solution was evaporated to
View All Related Papers

Articles

Silylation of Non-Steroidal Anti-Inflammatory Drugs

Results of a study involving the ability few Fluka silylating reagents to form GC-MS-compatible trimethylsilylmethyl derivatives of NSAIDs

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service