Skip to Content
MilliporeSigma

Skip To

C1357

Cholecalciferol

meets USP testing specifications

Synonym(s):

(+)-Vitamin D3, 7-Dehydrocholesterol activated, Activated 7-dehydrocholesterol, Calciol

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
250 mg

Estimated to ship onSeptember 30, 2027

$106.00
1 g

Estimated to ship onSeptember 30, 2027fromMILWAUKEE

$106.00

About This Item

Empirical Formula (Hill Notation):
C27H44O
CAS Number:
Molecular Weight:
384.64
NACRES:
NA.21
PubChem Substance ID:
eCl@ss:
34058003
UNSPSC Code:
12352205
EC Number:
200-673-2
MDL number:
Beilstein/REAXYS Number:
2339331

$106.00


Estimated to ship onSeptember 30, 2027Details


​
Request a Custom Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


Quality Segment

agency

USP/NF, meets USP testing specifications

assay

97.0-103.0%

form

crystalline

color

white

mp

83-86 °C (lit.)

application(s)

pharmaceutical (small molecule)

storage temp.

2-8°C

SMILES string

CC(C)CCC[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C

InChI

1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1

InChI key

QYSXJUFSXHHAJI-YRZJJWOYSA-N

Gene Information

human ... VDR(7421)

General description

Cholecalciferol (vitamin D3), a fat-soluble steroid is produced in the skin.

Application

Cholecalciferol has been used:
  • to induce arterial medial calcification (AMC) in mice
  • to study its impact in vascular remodeling associated with vascular calcification (VC) in murine model of obesity and insulin resistance (ob/ob mice)
  • to study its effect on anchorage dependent growth of RWPE2-W99 cells in monolayer culture

Biochem/physiol Actions

Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis.
Vitamin D acts through a receptor that modulates the proliferation and differentiation of both normal and cancer cells.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
C2100000C9756C9774
description

meets USP testing specifications

description

European Pharmacopoeia (EP) Reference Standard

description

≥98% (HPLC)

description

analytical standard

assay

97.0-103.0%

assay

-

assay

≥98% (HPLC)

assay

≥97.0%

form

crystalline

form

solid

form

powder

form

crystalline

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

-

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

2-8°C

Quality Level

200

Quality Level

-

Quality Level

200

Quality Level

200

mp

83-86 °C (lit.)

mp

83-86 °C (lit.)

mp

83-86 °C (lit.)

mp

83-86 °C (lit.)


Still not finding the right product?

Explore all of our products under Cholecalciferol


Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - STOT RE 1 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library




Questions

Reviews

No rating value

Active Filters