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G0625

D-(+)-Galactose

≥98% (HPLC)

Synonym(s):

Galactose

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Size/SKUAvailabilityPrice
100 g

Available to ship TODAY

$54.60
500 g

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$195.00
1 kg

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$323.00
5 kg

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$1,060.00

About This Item

Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
Molecular Weight:
180.16
UNSPSC Code:
12352201
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-416-4
Beilstein/REAXYS Number:
1724619
MDL number:

$54.60


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biological source

bovine (Ruminant- Cow, Ox, Buffalo)

Quality Segment

assay

≥98% (HPLC)

form

powder

technique(s)

HPLC: suitable, cell based assay: suitable

color

white to off-white

useful pH range

5.0-7 (25 °C, 180 g/L)

mp

168-170 °C (lit.)

solubility

water: 180 g/L at 20 °C (68 °F )

application(s)

cell analysis
genomic analysis
life science and biopharma

storage temp.

room temp

SMILES string

OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)C=O

InChI

1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4+,5+,6-/m0/s1

InChI key

GZCGUPFRVQAUEE-KCDKBNATSA-N

General description

D-Galactose, the C-4 epimer of glucose and a pivotal mammalian monosaccharide, is widely present in blood, milk, gangliosides, and N- and O-linked glycans. It is ubiquitous in both plants and animals and acts as a constituent in diverse polysaccharides, including galactomannans, carrageenans, Agar (L-Galactose), Hemicellulose, and galactans. As an aldohexose, it serves as an energy source and a crucial element in glycolipids and glycoproteins. D-galactose undergoes enzymatic conversion into D-glucose for metabolism or polysaccharide storage, representing a C-4 epimer of glucose.

Furthermore, galactose is a fundamental component of the disaccharide lactose and is released through hydrolysis by β-galactosidase enzymes, playing a vital role in the survival and virulence of bacteria. In Escherichia coli, galactose is utilized through the Leloir pathway, with β-d-galactose serving as a carbon source and β-d-galactose inducing UDP-galactose synthesis for biosynthetic glycosylation. Galactose finds applications in researching metabolic disorders like galactosemia and serves as a substrate for enzymes involved in galactose catabolism, making it a valuable component in galactosyltransferase labeling buffer and a supplement in MRS broth for the growth of thermophilic lactobacilli.

Application

D-(+)-Galactose has been used:
  • as a supplement in SGal media to grow yeast strains to examine the role of different Ssa heat-shock proteins (Hsp70) isoforms in Hsp90 chaperoning functions
  • as a carbon source in Biolog (MT2) microplate assay to test the ability of isolates to utilize carbon substrates
  • to induce expression of membrane protein-green fluorescent protein (GFP) fusion in yeast

D-Galactose is an energy source and a metabolite that finds application in cell biology, metabolomics and biochemical research.

Biochem/physiol Actions

Galactose is a simple monosaccharide that serves as an energy source and as an essential component of glycolipids and glycoproteins. Galactose contributes to energy metabolism via its conversion to glucose by the enzymes that constitute the Leloir pathway. Defects in the genes encoding these proteins lead to the metabolic disorder galactosemia.
Metabolism of D-galactose leads to the formation of reactive oxygen species (ROS) and results in oxidative stress and hepatocyte damage.

Features and Benefits

  • Ideal for Metabolomics, Biochemical and Cell Biology research
  • Versatile and adaptable for wide variety of laboratory and research applications

Other Notes

For additional information on our range of Biochemicals, please complete this form.
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

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This Item
48260G5388G0750
description

≥98% (HPLC)

description

suitable for microbiology, ≥99.0%

description

≥99% (HPLC), BioReagent, suitable for cell culture, suitable for insect cell culture

description

≥99% (HPLC)

technique(s)

cell based assay: suitable, HPLC: suitable

technique(s)

-

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable

technique(s)

HPLC: suitable

assay

≥98% (HPLC)

assay

≥99.0% (sum of enantiomers, HPLC)

assay

≥99% (HPLC)

assay

≥99% (HPLC)

biological source

bovine (Ruminant- Cow, Ox, Buffalo)

biological source

-

biological source

-

biological source

bovine (Ruminant- Cow, Ox, Buffalo)

Quality Level

300

Quality Level

200

Quality Level

300

Quality Level

300

solubility

water: 180 g/L at 20 °C (68 °F )

solubility

H2O: 0.1 g/mL, clear, colorless

solubility

H2O: 100 mg/mL

solubility

H2O: soluble 100 mg/mL, clear, colorless

form

powder

form

powder

form

powder

form

powder


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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



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Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Hi, What is the shelf-life of a 1 M aqueous galactose solution at refrigerated storage?

    1 answer
    1. Unfortunately, the solution stability of this product in refrigerated temperature has not been determined for this product.

      Helpful?

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