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S3674

Succinic acid

BioXtra, BioRenewable, ≥99.0%

Sustainability features

Synonym(s):

Butanedioic acid

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Size/SKUAvailabilityPrice
100 g
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$52.50
250 g
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$115.00
1 kg
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$318.00

About This Item

Linear Formula:
HOOCCH2CH2COOH
CAS Number:
Molecular Weight:
118.09
UNSPSC Code:
12352106
NACRES:
NA.25
PubChem Substance ID:
EC Number:
203-740-4
Beilstein/REAXYS Number:
1754069
MDL number:
Assay:
≥99.0%

$52.50


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Quality Segment

product line

BioXtra

assay

≥99.0%

sustainability

Sustainability features

impurities

≤0.01% Insoluble matter

ign. residue

≤0.02%

bp

235 °C (lit.)

mp

184-186 °C (lit.)

solubility

H2O: 0.5 M, clear, colorless

anion traces

chloride (Cl-): ≤0.001%, sulfate (SO42-): ≤0.003%

cation traces

Al: ≤0.0005%, Ca: ≤0.001%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH4+: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%

greener alternative category

SMILES string

OC(=O)CCC(O)=O

InChI

1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)

InChI key

KDYFGRWQOYBRFD-UHFFFAOYSA-N

General description

This product aligns with one or more of the 12 Principles of Green ChemistryThis product is biobased and thus aligns with "Use of Renewable Feedstocks". Click here for more information.

Application

Succinic acid has been used:
  • in succinate dehydrogenase mitochondrial assay.
  • as an internal standard in mass spectroscopy.
  • as succinate dehydrogenase substrate in oxygraph analysis to measure respiration rates.

Biochem/physiol Actions

Succinic acid is a byproduct of anaerobic fermentation in microbes. It is a dicarboxylic acid and an intermediate in Kreb′s cycle. Polymorphism in succinate dehydrogenase leads to succinate accumulation. High levels of succinate impairs 2-oxoglutarate epigenetic signalling. Succinate levels may modulate tumor progression. Succinate inhibits histone demethylation and may contribute to epigenetic changes. Succinate is crucial for interleukin-1 β (IL-1β) synthesis during inflammation and immune signalling.

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1 of 1

This Item
PHR141879798714080
description

BioXtra, BioRenewable, ≥99.0%

description

Pharmaceutical Secondary Standard; Certified Reference Material

description

anhydrous, free-flowing, Redi-Dri™, ACS reagent, ≥99.0%

description

purum p.a., ≥99.0% (T)

assay

≥99.0%

assay

-

assay

≥99.0%

assay

≥99.0% (T)

Quality Level

200

Quality Level

300

Quality Level

200

Quality Level

200

solubility

H2O: 0.5 M, clear, colorless

solubility

-

solubility

methanol: soluble 0.4 g/10 mL

solubility

methanol: soluble 0.4 g/10 mL

mp

184-186 °C (lit.)

mp

184-186 °C (lit.)

mp

184-186 °C (lit.)

mp

185-188 °C, 184-186 °C (lit.)

bp

235 °C (lit.)

bp

235 °C (lit.)

bp

235 °C (lit.)

bp

235 °C (lit.)

cation traces

Ca: ≤0.001%, Pb: ≤0.001%, Al: ≤0.0005%, Mg: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, Zn: ≤0.0005%, NH4+: ≤0.05%, Na: ≤0.005%, K: ≤0.005%

cation traces

-

cation traces

Fe: ≤5 ppm, heavy metals: ≤5 ppm (by ICP)

cation traces

Cu: ≤50 mg/kg, Ca: ≤50 mg/kg, Fe: ≤50 mg/kg, Na: ≤100 mg/kg, Pb: ≤50 mg/kg, Co: ≤50 mg/kg, Cd: ≤50 mg/kg, K: ≤100 mg/kg, Ni: ≤50 mg/kg, Zn: ≤50 mg/kg


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Pictograms

Corrosion

Signal Word

Danger

Hazard Codes

Precautionary Statements

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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