Key Documents

Dansylcadaverine

Name: Dansylcadaverine
Brand: SIGMA
Price: 57.5 USD
Availability: InStock

BioReagent, suitable for fluorescence, ≥99.0% (HPLC)

Synonym(s):

N-(5-Aminopentyl)-5-dimethylaminonaphthalene-1-sulfonamide, N-(Dimethylaminonaphthalenesulfonyl)-1,5-pentanediamine, Monodansyl cadaverine

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Size/SKU	Availability	Price
100 mg	Available to ship TODAYfromMILWAUKEE	$57.50
1 g	Estimated to ship onNovember 03, 2026fromMILWAUKEE	$281.00

About This Item

Empirical Formula (Hill Notation):

C₁₇H₂₅N₃O₂S

CAS Number:

10121-91-2

Molecular Weight:

335.46

UNSPSC Code:

12352108

NACRES:

NA.32

PubChem Substance ID:

57648439

EC Number:

233-326-9

Beilstein/REAXYS Number:

2951070

MDL number:

MFCD00042704

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Properties

product line

BioReagent

Quality Segment

100

assay

≥99.0% (HPLC)

technique(s)

protein detection: suitable

mp

137-140 °C

fluorescence

λ_ex 335 nm; λ_em 518 nm in methanol, λ_ex 338 nm; λ_em 500 nm (Reaction product)

suitability

suitable for fluorescence

storage temp.

−20°C

SMILES string

CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCCCN

InChI

1S/C17H25N3O2S/c1-20(2)16-10-6-9-15-14(16)8-7-11-17(15)23(21,22)19-13-5-3-4-12-18/h6-11,19H,3-5,12-13,18H2,1-2H3

InChI key

MLEBFEHOJICQQS-UHFFFAOYSA-N

Description

Application

Dansylcadaverine (MDC), an autofluorescent dye, is used to monitor autophagy. MDC accumulates in autophagic vacuoles due to a combination of ion trapping and specific interactions with membrane lipids.

Biochem/physiol Actions

Inhibitor of the fibrin-stabilizing fator; Inhibitor of epidermal growth factor (EGF) internalization; Fluorescent substrate for the assay of transamidating enzymes.

The autofluorescent dye dansylcadaverine, or monodansylcadaverine (MDC), is commonly used to monitor autophagy. MDC preferentially accumulates in autophagic vacuoles due to a combination of ion trapping and specific interactions with membrane lipids.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

air sensitive, handled under inert gas

Other Notes

Solubility of dansylcadaverine is tested in methanol (10 mg/mL). It has also been reported that dansylcadaverine is soluble in DMSO and acetic acid.

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Show Differences

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This Item	D4008	52063	33220
Sigma-Aldrich 30432 Dansylcadaverine	Sigma-Aldrich D4008 Dansylcadaverine	Supelco 52063 Cadaverine	Sigma-Aldrich 33220 Cadaverine dihydrochloride
description BioReagent, suitable for fluorescence, ≥99.0% (HPLC)	description ≥97% (TLC)	description analytical standard	description ≥99.0% (AT)
suitability suitable for fluorescence	suitability -	suitability -	suitability -
fluorescence λ_ex 338 nm; λ_em 500 nm (Reaction product), λ_ex 335 nm; λ_em 518 nm in methanol	fluorescence -	fluorescence -	fluorescence -
storage temp. −20°C	storage temp. −20°C	storage temp. -	storage temp. -
assay ≥99.0% (HPLC)	assay ≥97% (TLC)	assay 96.5-103.5% (T), ≥96.5% (GC)	assay ≥99.0% (AT)
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 200
product line BioReagent	product line -	product line -	product line -

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Pictograms

GHS07

Signal Word

Warning

Hazard Codes

H315,H319,H335

Precautionary Statements

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves

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