Skip to Content
MilliporeSigma

Skip To

62310

Lipase from Rhizopus niveus

powder (fine), ≥1.5 U/mg

Synonym(s):

Triacylglycerol acylhydrolase, Triacylglycerol lipase

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice
10 g
Check Cart for Availability
$69.10
50 g
Check Cart for Availability
$248.00

About This Item

CAS Number:
UNSPSC Code:
12352204
NACRES:
NA.26
EC Number:
232-619-9
EC Number:
MDL number:
Specific activity:
≥1.5 U/mg
Biological source:
fungus (Rhizopus niveus)

$69.10


Check Cart for Availability

​
Request a Custom Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


biological source

fungus (Rhizopus niveus)

Quality Segment

form

powder (fine)

specific activity

≥1.5 U/mg

mol wt

Mr ~83000

storage temp.

2-8°C

InChI

1S/C11H9N3O2.Na/c15-8-4-5-9(10(16)7-8)13-14-11-3-1-2-6-12-11;/h1-7,16H,(H,12,14);/q;+1/b13-9-;

InChI key

QWZUIMCIEOCSJF-CHHCPSLASA-N

General description

Lipases hydrolyze ester bonds of triacylglycerols and in some conditions, catalyze the synthesis of ester bonds by transesterification. Lipase from Rhizopus niveus exists as a single polypeptide chain with a molecular mass of about 30-34kDa.

Application

Lipase from Rhizopus niveus has been used to determine the positional distribution of fatty acids within triacylglycerol by hydrolysis of the acyl ester linkage at C-1 and C-3. It has also been used to induce intragastric lipolysis and study its effects on felodipine (a medication) release from a hydrophilic, extended release tablet.

Biochem/physiol Actions

Lipase from Rhizopus niveus is specifically used to produce cocoa butter substitutes.
Tri-, di-, and monoglycerides are hydrolyzed (in decreasing order of rate).

Other Notes

Substrate specificity: preferentially hydrolyzes the 1- and 3-positions(middle to long fatty acids); optimum pH 5.0-7.0; optimum temperature 30-45°C; Selective enzymatic removal of protecting functions (C-terminal COOH function)
1 U corresponds to the amount of enzyme which liberates 1 μmol fatty acid from a triglyceride per minute at pH 7.7 and 40°C (olive oil as substrate)]; 300 U as described above are equivalent to ~1 U using triolein, Cat. No. 62314, at pH 8.0 and 40°C as substrate.
Note: When triacetin is used as substrate, the pH is 7.4. Incubation time: 60 minutes.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
62305L9031L0777
description

powder (fine), ≥1.5 U/mg

description

powder (fine), ~10 U/mg

description

lyophilized powder, ≥4,000 units/mg solid (using olive oil)

description

solution, ≥100,000 U/g, white, beige

specific activity

≥1.5 U/mg

specific activity

~10 U/mg

specific activity

≥4,000 units/mg solid (using olive oil)

specific activity

≥100,000 U/g

biological source

fungus (Rhizopus niveus)

biological source

-

biological source

-

biological source

Aspergillus sp. (Aspergillus oryzae)

form

powder (fine)

form

powder (fine)

form

lyophilized powder

form

solution

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

mol wt

Mr ~83000

mol wt

Mr ~43000

mol wt

-

mol wt

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200


Pictograms

Health hazard

Signal Word

Danger

Hazard Codes

Precautionary Statements

Hazard Classifications

Resp. Sens. 1

Storage Class

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library




Questions

Reviews

No rating value

Active Filters